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Table 1 Genes deregulated in livers of both 3 and 12 months mice exposed to U and D waters

From: Cross-species toxicogenomic analyses and phenotypic anchoring in response to groundwater low-level pollution

Transcripts Cluster Id

Gene name

Gene description

Fold change

  

3 months

12 months

  

U vs Ctrl

D vs Ctrl

U vs Ctrl

D vs Ctrl

10603833

Usmg5

Upregulated during skeletal muscle growth 5

-4.53

-4.28

-2.83

-2.95

10374476

Rps17

Ribosomal protein S17

-2.96

-3.19

-1.85

-1.89

10357242

Dbi

Diazepam binding inhibitor

-2.87

-2.71

-1.84

-2.23

10387816

Rnasek

Ribonuclease, RNase K

-2.17

-2.33

-1.61

-1.78

10344817

Cspp1

Centrosome and spindle pole associated protein 1

-1.75

-1.62

-1.80

-2.38

10483809

Nfe2l2

Nuclear factor, erythroid derived 2, like 2

-1.66

-1.78

-1.71

-1.81

10500798

  

-1.57

-1.78

-2.75

-2.78

10598089

mt-Te

tRNA glutamic acid, mitochondrial

2.12

2.47

4.20

5.01

10598087

ND6

NADH dehydrogenase subunit 6

2.82

3.37

1.86

3.73

10598073

mt-Tq

tRNA glutamine, mitochondrial

4.07

5.85

5.67

7.28

10528191

Speer4d|Speer4c|Speer4e|

Spermatogenesis associated glutamate (E)-rich protein 4d/4c/4e

4.13

4.67

1.65

1.80

10598083

mt-Ts1

tRNA serine 1, mitochondrial

5.32

6.71

3.00

4.83

10598091

mt-Tp

tRNA proline, mitochondrial

5.62

7.62

3.11

3.85

10598075

mt-Ta

tRNA alanine, mitochondrial

5.93

7.82

16.92

26.75

10598023

mt-Tv

tRNA valine, mitochondrial

6.17

6.69

4.21

5.75

10519811

Speer8-ps1|Speer7-ps1

Spermatogenesis associated glutamate (E)-rich protein 7/8, pseudogene 1

6.34

6.92

3.13

3.88

10598057

mt-Tr

tRNA arginine, mitochondrial

6.40

7.63

10.12

28.13

10436773

Gm7735|Gm9789

 

6.48

6.90

3.75

3.25

10412517

Gm3002|Gm10021|Gm3512

 

7.66

10.80

3.88

4.55

10582888

  

7.70

9.65

2.83

5.64

10598081

mt-Ty

tRNA tyrosine, mitochondrial

10.46

13.91

6.51

10.49

10598079

mt-Tc

tRNA cysteine, mitochondrial

10.88

15.64

4.72

7.30

10598018

mt-Tf

tRNA phenylalanine, mitochondrial

11.56

14.23

14.71

27.37

10598062

mt-Th

tRNA histidine, mitochondrial

13.20

15.78

27.68

46.30

10598077

mt-Tn

tRNA asparagine, mitochondrial

21.72

32.04

6.55

9.85

10598041

mt-Tk

tRNA lysine, mitochondrial

24.14

28.86

39.43

66.79

10598071

mt-Tt

tRNA threonine, mitochondrial

27.51

35.77

7.81

15.37

10598064

mt-Tl2

tRNA leucine 2, mitochondrial

58.00

70.56

44.83

70.91

10353034

Snord87

Small nucleolar RNA, C/D box 87

-3.20

-3.39

2.83

2.77

10398451

Rps25|Gm4963

Ribosomal protein S25 | predicted gene 4963

-1.70

-1.81

1.75

1.80

10465831

5730408K05Rik

RIKEN cDNA 5730408 K05 gene

-2.26

-2.30

4.41

4.10

  1. In bold, genes inversely deregulated in the two data sets. mt- stays for mitochondrial.
  2. The arithmetic fold change is reported.