Variation in CRISPR/Cas locus in L. crispatus. The arrows represent different genes and their orientation within a locus. Orthologous genes are positioned vertically. The cas genes with conserved function are of the same color, whereas grey describes genes not matching a Cas model. Outlines of genes orthologous to some cas gene, but not matching a Cas model are color coded according to the ortholog groups. Dashed lines represent contig breaks. Diamonds represent direct repeats and boxes different spacer sequences. Identical spacers are represented by the same color. The direct repeats of the top nine genomes are identical.