Figure 7

Summary of the “PPARα tailored analysis”. Genes selected for the “PPARα-tailored analysis” were annotated using GeneCards and grouped into functional categories such as “peroxisomes”, “mitochondria” etc. The total number of significantly up- and down-regulated genes found per category in in vitro, ex vivo, and in vivo models is represented by horizontal bars. Bars located >0 on Y axis show number of upregulated genes and bars located <0 on Y axis show number of downregulated genes. In vitro represents primary hepatocytes treated with Wy14643 for 24 h, ex vivo - precision cut liver slices treated with Wy14643 for 24 h and in vivo - livers of mice treated with Wy14643 for 5 days.