Figure 1

Euclidean distance in 2D NMDS space as a function of bit score (top) and phylogenetic distance (bottom). Euclidean distance was compared to bit score and phylogenetic distance to evaluate the fidelity of these parameters. Euclidean distance in the FA_desaturase pfam is strongly correlated with bit score (R² = 0.4232 n = 2,439,512), obtained from reciprocal blast, and with phylogenetic distance (R² = 0.5029, n = 2,439,512), as summed branch lengths from a maximum-likelihood tree. Orange lines are linear models fit to the complete data sets; only 10,000 randomly selected data points are plotted.