Figure 1From: Chromosome microarray testing for patients with congenital heart defects reveals novel disease causing loci and high diagnostic yieldDistribution of the 89 sub-chromosomal genomic imbalances detected in this study among patients with CHD. Chromosomal loci 22q11.21 and 8p23.1 were two known pathogenic CNV hotspots in CHD patients. This study also identified deletions at loci 4q terminal, 15q11.2, 16p12.1 and Yp11.2 as potential pathogenic hotspots.Back to article page