Gene | Short name | Log-FC head kidney | Log-FC spleen | Log-FC pyloric caeca | Category | Associated function |
---|---|---|---|---|---|---|
MHC class I antigen | MHC I | -6.3 | -4.9 | -5.4 | 1 | Antigen processing and presentation |
Interferon regulatory factor 7 | IFR7 | -1.8 | -1.6 | -3.6 | 1 | Positive regulation of interferons production |
Interferon-induced protein 44 | IFI44 | -3.2 | -3.6 | -2.2 | 1 | Interferon-inducible protein |
Interferon-induced protein with tetratricopeptide repeats 1 | IFIT-1 | -4.7 | -5.0 | -2.1 | 1 | Interferon-inducible protein |
Gig2-like protein | Gig2 | -10.4 | -12.8 | -7.4 | 1 | Interferon-inducible protein |
Interferon gamma receptor alpha chain | IFNGR1 | -2.7 | -4.4 | -- | 1 | Regulation of interferon-gamma-mediated signalling pathway |
Interferon regulatory factor 3 | IFR3 | -1.8 | -2.1 | -- | 1 | Positive regulation of interferons production |
Toll-like receptor 9 | TLR9 | -3.0 | -3.0 | -- | 1 | Innate immune response; Positive regulation of interferons production |
Mannose-binding lectin-associated serine protease-3b | MASP3b | 7.6 | 4.9 | 4.5 | 1 | Complement activation |
Epidermis-type lipoxygenase 3-like | ALOXE3 | 5,7 | 6.8 | 10.3 | 1 | Leukotriene metabolic process |
L-amino-acid oxidase-like | IL4I1 | 4.8 | 5.9 | 9.5 | 1 | Innate immune response |
Interleukin-17a f-1 | IL-17A/F-1 | -- | -- | -3.8 | 1 | Inflammatory response |
Interleukin-22 | IL22 | -4.5 | -- | -1.7 | 1 | Inflammatory response |
CD83 antigen | CD83 | -- | -1.8 | 2.5 | 1 | Defence response |
CD209 antigen-like | CD209 | -- | -4.3 | 2.2 | 1 | Innate immune response |
Cytochrome b-245 heavy chain | CYBB | -4.0 | -- | 3.7 | 1 | Inflammatory response |
CC chemokine | CCL | -- | 1.9 | 4.0 | 1 | Inflammatory response |
Interleukin-1 receptor accessory protein | IL1RAP | -- | -4.2 | 2.6 | 1 | Inflammatory response |
Lipopolysaccharide-induced tumor necrosis factor-alpha factor | LITAF | -- | -1.6 | 6.2 | 1,2 | Regulation of cytokine production-Apoptotic process |
Immunoglobulin light chain | IGlc | -1.8 | -2.0 | 2.7 | 1 | Antigen binding |
T-cell surface glycoprotein cd4 | CD4 | -- | -1.6 | -- | 1 | T cell receptor signalling pathway |
T-cell receptor beta chain | TCRB | -- | -2.0 | -- | 1 | T cell receptor signalling pathway |
Perforin-1-like | PRF1 | -3.2 | -- | -- | 1 | T cell-mediated cytolysis |
Granzyme A/K | GZM-A/K | -1.7 | -- | -- | 1 | T cell-mediated cytolysis |
Catalase | CAT | -2.0 | -1.8 | -2.5 | 1 | Hydrogen peroxide catabolic process |
Superoxide dismutase | SOD | -- | -- | -2.1 | 1 | Removal of superoxide radicals |
Glutathione s-transferase theta-1 | GSTT1 | -- | -- | -2.0 | 1 | Oxidation-reduction process |
Caspase-3-like | CASP3 | -- | -- | 5.5 | 2 | Positive regulation of apoptotic process |
Cytochrome c | CYTC | 2.5 | -- | 4.3 | 2 | Apoptotic DNA fragmentation |
TNF receptor-associated factor 2-like | TRAF2 | -- | -- | 3.6 | 2 | Regulation of apoptotic process |
Tumor necrosis factor receptor superfamily member 10b-like | TNFRSF10B | -3.2 | -2.2 | 2.6 | 2 | Regulation of apoptotic process |
Hemoglobin subunit alpha-d | HBAD | -5.2 | -3.5 | -- | 3 | Oxygen transport |
Hemoglobin subunit beta-2 | HBB2 | -4.7 | -3.8 | -- | 3 | Oxygen transport |
Hemoglobin subunit beta-1 | HBB1 | -4.6 | -3.2 | -- | 3 | Oxygen transport |
Band 3 anion exchange protein | SLC4A1 | -6.6 | -4.5 | -- | 3 | Erythrocytes differentiation |
Gata-binding factor 2-like | GATA2 | -3.5 | -2.2 | -- | 3 | Erythrocytes differentiation |
Mitoferrin-1 | SLC25A37 | -3.6 | -3.5 | -- | 3 | Erythrocytes maturation |
T-cell acute lymphocytic leukemia protein 1 | TAL1 | -2,8 | -1,6 | -- | 3 | Erythrocytes differentiation- Erythrocytes maturation |
Hepcidin | HEPC | 2.7 | 2.0 | -- | 3 | Iron metabolism |
Aminopeptidase n | ANPEP | 2.2 | 7.3 | -9.2 | 4 | Protein metabolic process |
Intestinal-type alkaline phosphatase 1 | ALPI | -- | -- | -11.7 | 1,4 | Metabolic process |
Acidic mammalian chitinase | CHIA | -- | -- | -14.1 | 4 | Carbohydrate metabolic process |
Apolipoprotein a-iv precursor | APOA4 | -- | -- | -6.5 | 4 | Lipoprotein metabolic process |
Gastric inhibitory polypeptide | GIP | -- | -- | -3.1 | 4 | Response to nutrient levels |
Cocaine- and amphetamine-regulated transcript | CART | -- | -- | 6.7 | 4 | Negative regulation of appetite |
Gastrin cholecystokinin-like peptide | GAST-CCK | -- | -- | -4.4 | 4 | Digestion |
Collagen alpha-2 chain | COL1A2 | -2.0 | -1.5 | -2.4 | 5 | Extracellular matrix structural constituent |
Tropomodulin 4 | TMOD4 | -5.6 | -3.9 | -2.3 | 5 | Tropomyosin binding |
Formin-like protein 1-like | FMNL1 | -4.0 | -3.0 | -2.8 | 5 | Actin cytoskeleton organization |
Alpha actin | ACTA | -3.9 | -- | -2.7 | 5 | Skeletal muscle fiber development |