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Table 2 Map-corrected, non-local genomic windows with significant enrichment for detected transposon insertions in unselected tissues (liver, lung, skin, spleen)

From: Sequencing methods and datasets to improve functional interpretation of sleeping beauty mutagenesis screens

Window coordinates

p-value

Identified by initial analysis?

# of tissues with insertions

# of strains with insertions

Gene within window

Other notes

chr2:81,670,001-81,690,000

3.39E-07

No

3

3

  

chr5:28,160,001-28,180,000

<1.00E-300

Yes

4

4

En2

Transposon artifact1

chr5:113,680,001-113,700,000

7.91E-18

Yes

4

3

1700069L16Rik

 

chr6:12,510,001-12,530,000

<1.00E-300

Yes

4

4

Thsd7a

 

chr6:12,530,001-12,550,000

<1.00E-300

Yes

4

4

Thsd7a

 

chr6:12,550,001-12,570,000

<1.00E-300

Yes

4

3

Thsd7a

 

chr8:65,840,001-65,860,000

7.21E-11

Yes

4

3

March1

 

chr10:36,800,001-36,820,000

3.34E-15

Yes

4

4

Hs3st5

 

chr11:3,180,001-3,200,000

5.64E-176

Yes

4

4

Sfi1

Genome assembly artifact2

chr11:76,780,001-76,800,000

3.30E-45

Yes

4

4

Cpd

 

chr11:79,420,001-79,440,000

1.88E-09

Yes

4

3

Nf1

 

chr13:15,380,001-15,400,000

1.95E-07

No

4

4

  

chr13:31,620,001-31,640,000

1.01E-200

Yes

4

4

Foxf2

Transposon artifact1

chr16:28,880,001-28,900,000

5.71E-09

Yes

4

3

Mb21d2

 

chr17:83,160,001-83,180,000

2.93E-08

No

4

3

  

chrX:150,970,001-150,990,000

2.26E-07

No

3

4

Gnl3l

 
  1. 1Detected as significant due to the inclusion of En2 and Foxf2 splicing elements within the transposon structure.
  2. 2Detected as significant due to presence at a higher copy number than annotated in the reference genome.