Figure 5

Chromosome 16p13.11 deletion associated with SNHL. a. The frequencies of the deletion on chromosome 16 encompassing part of the PDXDC1 gene are indicated for the entire sample set, as well as separated out for the affected individuals and controls (highlighted in the black box). Green shading indicates duplications whereas red shading indicates deletions. The horizontal tracks indicate the coordinates of the position along chromosome 16p13.11 (hg18). Gene and exon tracks are included. b. The frequencies of the deletion among the various ethnic groups; African, Caucasian, East Asian, Mexican, and Native American. Frequencies were calculated separately for CNVs called by both algorithms and for CNVs called by one algorithm (Nexus) only.