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Figure 2 | BMC Genomics

Figure 2

From: The translation initiation complex eIF3 in trypanosomatids and other pathogenic excavates – identification of conserved and divergent features based on orthologue analysis

Figure 2

Conserved and diverged features between eIF3b orthologues from various protozoan and multicellular organisms. A Schematic representation of T. brucei EIF3B. The RRM and WD domains and the putative eIF3i binding region are indicated by red, green and blue boxes, respectively. B Amino acid sequence alignment comparing the RRM and WD domains and eIF3i binding region from eIF3b homologue from various protozoan and multicellular eukaryotes. The alignment was carried out as described for Figure 1 and the three segments analyzed are indicated by the red, green and blue lines, respectively. The “#” symbol marks the position of the conserved aromatic residue required for the interaction with yeast eIF3i [44], whilst the position of other residues seen to be involved in the interaction of eIF3b with eIF3i in yeast are indicated by the “+” symbol.

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BMC Genomics

ISSN: 1471-2164

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