Figure 4

Example fractions of miRNA-mRNA pairs satisfying the correlation threshold. Type Lgen MTBs were identified from the high-confidence expression union set of miRNA-target interactions with TarBase inputs. For each MTB, the fraction of miRNA-mRNA pairs with expression correlation more negative than t=−0.2 among the 10 cell lines was computed. The distribution of these fractional values is shown by a histogram. Also shown are the distributions of fraction values for random groups of miRNAs and mRNAs of the same sizes as the MTBs, and for groups of miRNAs and their target mRNAs not within same MTBs.