Skip to main content

Table 2 Illustrating examples of using MTBs to functionally annotate miRNAs

From: Systematic exploration of autonomous modules in noisy microRNA-target networks for testing the generality of the ceRNA hypothesis

Enriched GO term
MTB ID Total number of mRNAs mRNAs annotated with the GO term miRNAs
GO:0004674 Protein serine/threonine kinase activity
1 4 AAK1, MAPK1, PDK3 miR-17, miR-20b, miR-93, miR-320a
GO:0000792 Heterochromatin
2 4 CBX5, HMGA2, RNF20 let-7b, let-7c, let-7d, let-7e, let-7g, miR-185
GO:0007219 Notch signaling pathway
3 3 CDK6, TNRC6B miR-15a, miR-34a, miR-449a, miR-497
GO:0043161 Proteasome-mediated ubiquitin-dependent
protein catabolic process
4 19 EDEM1, UBE2W, WWP2 miR-25, miR-32, miR-363
  1. Each row corresponds to one example MTB.