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Table 4 Biological process (BP) terms and annotation clusters significantly down-regulated due to the main effect of age

From: Transcriptional markers of sub-optimal nutrition in developing Apis mellifera nurse workers

Cluster

Description

N

X 2 adj A

OrthologuesB

GO:0005524

ATP binding (MF)

10

0.0029

FBgn0260990, FBgn0261014, FBgn0032243, FBgn0025743, FBgn0026059, FBgn0000723, FBgn0030343, FBgn0015615, FBgn0036486, FBgn0051729

Kegg:03040

Spliceosome

3

0.0099

FBgn0031390, FBgn0038927, FBgn0031266

GO:0007391

Dorsal closure (BP)C

3

0.0048

FBgn0010434, FBgn0000723, FBgn0044323

IPR001680, IPR011046, IPR019775

WD40 repeat, WD40 repeat-like-containing domain, WD40 repeat, conserved site

5

<0.0001

FBgn0037758, FBgn0029903, FBgn0044323, FBgn0038927, FBgn0043362

IPR001680, IPR011046, IPR019775, IPR020472, IPR019782, IPR017986, IPR019781

WD40 repeat, WD40 repeat-like-containing domain, WD40 repeat, conserved site, G-protein beta WD-40 repeat, WD40 repeat 2, WD40-repeat-containing domain, WD40 repeat, subgroup

4

<0.0001

FBgn0029903, FBgn0044323, FBgn0038927, FBgn0043362

IPR011046

WD40 repeat-like-containing domain

6

<0.0001

FBgn0037758, FBgn0029903, FBgn0024698, FBgn0044323, FBgn0038927, FBgn0043362

GO:0003779

Actin binding (MF)

3

0.0109

FBgn0035347, FBgn0010434, FBgn0029903

IPR016024

Armadillo-type fold

4

0.0248

FBgn0260990, FBgn0030674, FBgn0043362, FBgn0031266

GO:0016319

Mushroom body developmentD

2

0.0071

FBgn0025743, FBgn0010051

GO:0007030

Golgi organizationD

2

0.0019

FBgn0261014, FBgn0033075

  1. AX2adj refers to the significance of the Fisher’s exact test with a Benjamini-Hochberg correction for multiple comparisons.
  2. BOrthologues represent Drosophila melanogaster genes similar to the differentially expressed transcripts discovered in the present study that are listed in FlyBase.
  3. CTerms that were significant BP terms and were part of a significant gene annotation cluster.
  4. DTerms that represented significant BP terms but did not form a significant gene annotation cluster.