Table 1 Functional roles of genes hosting adipose core miRNAs in lipid metabolism
From: MicroRNAs in bovine adipogenesis: genomic context, expression and function
Functions annotation | p-Value | Molecules |
|---|---|---|
Concentration of lipid | 5.72E-07 | EP300 (miR-1281), PDGFRB (miR-1777b), PPARGC1B (miR-378), PTK2 (miR-151-5p), SREBF2 (miR-33a) |
Concentration of phosphatidic acid | 4.74E-06 | EP300 (miR-1281), PDGFRB (miR-1777b), PTK2 (miR-151-5p) |
Quantity of phosphoinositide | 1.59E-04 | PDGFRB (miR-1777b), PTK2 (miR-151-5p) |
Quantity of myristic acid | 9.03E-04 | PPARGC1B (miR-378) |
Quantity of sn-glycero-3-phosphocholine | 9.03E-04 | EP300 (miR-1281) |
Oxidation of lipid | 1.47E-03 | PPARGC1B (miR-378), SREBF2 (miR-33a) |
Concentration of palmitic acid | 1.81E-03 | PPARGC1B (miR-378) |
Concentration of stearic acid | 1.81E-03 | PPARGC1B (miR-378) |
Concentration of cholesterol | 2.98E-03 | PPARGC1B (miR-378), SREBF2 (miR-33a) |
Quantity of phosphatidylinositol-3-phosphate | 3.01E-03 | PDGFRB (miR-1777b) |
Storage of cholesterol | 4.51E-03 | SREBF2 (miR-33a) |
Uptake of palmitic acid | 4.51E-03 | PPARGC1B (miR-378) |
Metabolism of membrane lipid derivative | 5.82E-03 | PDGFRB (miR-1777b), SREBF2 (miR-33a) |
Quantity of phosphatidylinositol-3,4,5-triphosphate | 9.00E-03 | PTK2 (miR-151-5p) |
Synthesis of phosphatidylinositol-3,4,5-triphosphate | 1.05E-02 | PDGFRB (miR-1777b) |
Oxidation of palmitic acid | 1.20E-02 | PPARGC1B (miR-378) |
Accumulation of cholesterol | 1.47E-02 | SREBF2 (miR-33a) |
Synthesis of cholesterol | 1.73E-02 | SREBF2 (miR-33a) |
Synthesis of lipid | 2.15E-02 | PDGFRB (miR-1777b), SREBF2 (miR-33a) |
Homeostasis of cholesterol | 2.36E-02 | SREBF2 (miR-33a) |
Hydrolysis of phosphatidylinositol | 2.74E-02 | PDGFRB (miR-1777b) |