Figure 3
From: Unique features of the transcriptional response to model aneuploidy in human cells
Comparison of the Aneuploidy Response Pattern with transcriptional responses to stress stimuli. A. 2-dimensional pathway analysis comparison of HCT116-derived complex aneuploid cell line HPT1* and HCT116 treated with hydroxyurea. B. 2- dimensional pathway analysis comparison of HCT116-derived complex aneuploid cell line HPT2* and HCT116 treated with actinomycin D. C. 2-dimensional pathway analysis comparison of HCT116 with tetrasomy of chromosome 5 and HCT116 grown in medium with bafilomycin A1 D. Distance matrix of the Spearman rank correlation of aneuploid cell lines and HCT116 grown in stress-inducing conditions. Asterisks indicate the cell lines with H2B-GFP. Abbreviations: bafilo = bafilomycin; actino = actinomycin; HU = hydroxyurea; NO = nitric oxide; H2O2 = hydrogen peroxide; glc = glucose.