A genome-wide association study demonstrates significant genetic variation for fracture risk in Thoroughbred racehorses

Table 3 Logistic regression results for ECA 18 haplotype block 1

Haplotype	Odds ratio	t-statistic (Wald test)	P-value	Frequency in cases	Frequency in controls
GGAGGCTAAA	0.511	15	1 × 10^-4	0.738	0.856
TAGAACCGGG	1.42	3.66	0.161	0.196	0.130
TGGAATTAAG	3.39	5.41	0.042	0.029	0
GAGAACCGGG	1.8 × 10¹¹	2.51	0.286	0.024	0

Background of horse (flat or National Hunt-bred) and sex were fitted as covariates in the haplotype logistic regression option in PLINK, p-values were derived using 10,000 permutations.

ISSN: 1471-2164