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Table 2 The thirty most significantly associated probes to smoking status after genome-wide correction

From: The effect of smoking on DNA methylation of peripheral blood mononuclear cells from African American women

     Average beta values   
Probe ID Gene Placement Island status Smokers Non-smokers T-test Corrected p-value
cg19859270 GPR15 1stExon   0.77 0.87 2.44E-25 1.19E-19
cg05575921 AHRR Body N_Shore 0.68 0.83 2.54E-24 6.17E-19
cg08672695   N_Shelf 0.65 0.48 4.58E-20 7.40E-15
cg23576855 AHRR Body N_Shore 0.52 0.71 2.78E-17 3.37E-12
cg02657160 CPOX Body N_Shore 0.77 0.83 4.09E-17 3.97E-12
cg21161138 AHRR Body   0.62 0.70 5.74E-17 4.64E-12
cg18230367 RNASE4 TSS200 N_Shore 0.05 0.07 2.13E-16 1.48E-11
cg02319016 PAK2 5'UTR S_Shelf 0.70 0.56 1.53E-15 9.27E-11
cg26607002 NOSTRIN TSS200   0.68 0.63 4.31E-15 2.32E-10
cg04677326 C19orf28 TSS200 Island 0.17 0.15 4.98E-15 2.42E-10
cg01940273   Island 0.50 0.59 5.69E-15 2.51E-10
cg05457881 C6orf218 TSS1500   0.18 0.22 6.91E-15 2.79E-10
cg06126421    0.65 0.76 7.79E-15 2.91E-10
cg21566642   Island 0.38 0.48 8.62E-15 2.99E-10
cg13086586 PAICS Body S_Shore 0.17 0.23 3.26E-14 1.05E-09
cg15281724 TXLNB Body   0.78 0.69 9.63E-14 2.92E-09
cg15645254 NAALAD2 Body   0.78 0.75 1.23E-13 3.51E-09
cg19111030 ANKRD53 TSS1500 N_Shore 0.17 0.20 1.96E-13 5.30E-09
cg09741592 HNRNPA1 Body S_Shore 0.18 0.23 3.23E-13 8.25E-09
cg08528204 TMEM116 TSS1500 S_Shore 0.17 0.20 8.77E-13 2.07E-08
cg17391741   N_Shore 0.82 0.85 8.97E-13 2.07E-08
cg15614155   N_Shore 0.83 0.78 1.06E-12 2.34E-08
cg05916255 ABCC2 Body N_Shore 0.85 0.82 1.17E-12 2.47E-08
cg25223391 UVRAG Body   0.71 0.67 1.31E-12 2.52E-08
cg00736283 ASF1B TSS200 Island 0.13 0.11 1.32E-12 2.52E-08
cg26703534 AHRR Body S_Shelf 0.62 0.68 1.35E-12 2.52E-08
cg16851858   N_Shelf 0.73 0.77 1.55E-12 2.80E-08
cg02521854   N_Shelf 0.13 0.11 1.69E-12 2.93E-08
cg15658543 CARD11 5'UTR   0.88 0.85 1.91E-12 3.20E-08
cg13789443 GALNT11 5'UTR S_Shore 0.60 0.55 2.00E-12 3.24E-08
  1. All average methylation values are non-log transformed beta-values. Island status refers to the position of the probe relative to the island. Classes include: 1) Island, 2) N (north) shore, 3) S (south) shore, 4) N (north) shelf, 5) S (south) shelf and 6) blank denoting that the probe does not map to an island.