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Table 1 Common gene targets of all the up-regulated (FC > 5) miRNAs identified at 16 wks

From: Altered miRNA expression in canine retinas during normal development and in models of retinal degeneration

Gene target symbol Definition NCBI accession sequences
FBXO28 F-box protein 28 NM_015176; AK303381
BBX Bobby sox homolog (Drosophila) NM_020235; NM_001142568
SPRED1 Sprouty-related, EVH1 domain-containing protein 1 NM_152594
MMAA Methylmalonic aciduria (cobalamin deficiency) type A (mitochondrial) NM_172250
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 NM_005668
KCNK10 potassium channel, subfamily K, member 10 NM_021161; NM_138317
USP9Y Ubiquitin specific peptidase 9, Y-linked NM_004654
ALG11 Asparagine-linked glycosylation 11, alpha-1,2-mannosyltransferase homolog (Yeast) NM_001004127
DIEXF Digestive organ expansion factor homolog (Zebrafish) NM_014388; AK314061
RORA RAR-related orphan receptor A NM_002943; NM_134260
PHACTR2 Phosphatase and actin regulator 2 NM_014721; NM_001100164
SNTB2 Syntrophin, beta 2 (dystrophin-associated protein A1, 59 kDa, basic component 2) NM_006750
BCAT1 Branched chain amino-acid transaminase 1, cytosolic NM_005504; AK128527
PAG1 Phosphoprotein associated with glycosphingolipid microdomains 1 NM_018440
CREB1 cAMP responsive element binding protein 1 NM_004379; NM_134442
PTAR1 Protein prenyltransferase alpha subunit repeat containing 1 NM_001099666
TFCP2L1 Transcription factor CP2-like 1 NM_014553; AL137740
SLC1A2 Solute carrier family 1 (glial high affinity glutamate transporter), member 2 NM_004171; U01824
ACVR2B Activin A receptor, type IIB NM_001106; BC096245
ST8SIA3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 NM_015879
UBN2 Ubinuclein 2 NM_173569
ADCY1 Adenylate cyclase 1 (brain) NM_021116
DNAH14 Dynein, axonemal, heavy chain 14 NM_001373
SSR1 Signal sequence receptor, alpha NM_003144; CR599599
FUT9 Fucosyltransferase 9 (alpha (1,3) fucosyltransferase) NM_006581
SCAI Suppressor of cancer cell invasion NM_173690; NM_001144877
CDK6 Cyclin-dependent kinase 6 NM_001259; NM_001145306
TNRC6B Trinucleotide repeat containing 6B NM_015088; NM_001024843
LOC728264 Homo sapiens cDNA FLJ44517 fis, clone UTERU3002667 AK126481
CBX5 Chromobox homolog 5 NM_012117; NM_001127321
NSL1 Kinetochore-associated protein NSL1 homolog NM_015471; AK303250
KSR2 Kinase suppressor of ras 2 NM_173598
NEAT1 Nuclear paraspeckle assembly transcript 1 NR_028272
SH3TC2 SH3 domain and tetratricopeptide repeats 2 NM_024577; AB075865
TSIX X (inactive)-specific transcript, antisense NR_003255
  1. The complete list of DE miRNAs identified at 16 wks between xlpra2 and normal retinas is shown in Additional file 3. The 35 common gene targets are reported with their symbols, definitions, and NCBI accession numbers.