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Table 2 Differences between cancer and all other genes for 4 cancer gene predictors in 7 datasets

From: How to get the most from microarray data: advice from reverse genomics

Dataset Trait Mean CG Mean OG Z P value Rank
BC_GSE10780 -LOG(P) 6.09 5.84 2.89 0.003852 6
m(AN) 6.32 6.16 3.68 0.000233 4
m(T) 6.51 6.18 3.3 0.000967 5
FC 1.33 1.19 4.65 3.32E-06 3
sd(AN) 0.42 0.33 5.61 2.02E-08 1
sd(T) 0.62 0.45 5.37 7.87E-08 2
BC_GSE3716 -LOG(P) 0.62 0.64 1.04 0.29834 3
m(AN) 7.34 7.42 0.37 0.711382 6
m(T) 7.41 7.51 0.75 0.453255 4
FC 1.21 1.21 0.58 0.561915 5
sd(AN) 0.84 0.79 2.79 0.005271 2
sd(T) 0.89 0.81 3.55 0.000385 1
CC_GSE31737 -LOG(P) 3.51 2.53 4.64 3.48E-06 6
m(AN) 5.74 4.77 5.54 3.02E-08 5
m(T) 5.89 4.77 6.19 6.02E-10 4
FC 1.40 1.19 6.58 4.7E-11 2
sd(AN) 0.38 0.22 6.52 7.03E-11 3
sd(T) 0.56 0.24 7.53 5.07E-14 1
LC_GSE19188 -LOG(P) 6.55 5.37 1.15 0.250144 6
m(AN) 6.49 6.06 4.74 2.14E-06 4
m(T) 6.61 6.12 4,47 7.82E-06 5
FC 1.58 1.29 5.62 1.91E-08 3
sd(AN) 0.34 0.17 7.86 3.84E-15 2
sd(T) 0.93 0.56 10.77 4.77E-27 1
LC_GSE18842 -LOG(P) 5.98 4.31 3.08 0.00207 6
m(AN) 6.24 5.75 6.26 3.85E-10 4
m(T) 6.47 5.75 6.56 5.38E-11 3
FC 1.66 1.31 6.1 1.06E-09 5
sd(AN) 0.43 0.33 8.21 2.21E-16 2
sd(T) 0.75 0.47 8.72 2.78E-18 1
PC_GSE6919 -LOG(P) 2.28 1.75 3.62 0.000295 4
m(AN) 7.41 7.01 1.87 0.061484 5
m(T) 7.42 6.99 1.86 0.062886 6
FC 1.32 1.21 4,57 4.88E-06 2
sd(AN) 0.61 0.59 3.87 0.000109 3
sd(T) 0.74 0.64 4.71 2.48E-06 1
PC_GSE21034 -LOG(P) 2.55 1.68 3.97 7.19E-05 6
m(AN) 8.65 7.86 6.82 9.1E-12 4
m(T) 8.59 7.82 5.87 4.36E-09 5
FC 1.21 1.12 6.78 1.2E-11 3
sd(AN) 0.31 0.27 6.3 2.98E-10 3
sd(T) 0.37 0.28 6.83 8.49E-12 1
  1. CG, cancer genes; OG, other genes. Statistics from nonparametric Mann-Whitney test; rank, rank of the variable for a given dataset based on Z score; m(AN), mean expression in adjacent normal tissue: m(T), mean expression in tumor tissue; FC, fold change; SD(AN), standard deviation of the gene expression values in adjacent normal tissue; SD(T), standard deviation of the gene expression values in tumor tissue.