Figure 2
From: Cis-regulatory elements are harbored in Intron5 of the RUNX1gene
Identification of Conserved Non-coding Sequences (CNS) in intron 5 of the RUNX1 Gene. Top panel shows the genomic organization of the RUNX1 gene. Middle panel correspond to visualization of sequence alignment outputs for comparison of intron 5 sequence among mouse-human and rat-human using AVID and PROLAGAN alignment methods respectively. Bottom panel correspond to an schematic representation of the identified CNS and also their relative position to the breakpoint cluster regions (BCRs) mapped for t(8;21) are indicated.