Table 4 Detailed information on the reported QTLs containing the 31 differentially expressed genes between the mammary gland of two cows with high milk protein and fat percentage and two cows with low protein and fat percentage
Gene name | Position (bp) | Position (cM)1 | Previously reported QTL | |||
|---|---|---|---|---|---|---|
| Â | Distance to QTL peak (cM) | CI and peak location (cM) | Trait | References | ||
SAA3 | 26668046–26671801 | Chr29: 36.8 | 12.6 | Peak: 24.2 | PP | Bagnato et al., J Dairy Sci, 2008 [33] |
HEATR7B2 | 33456348–33528569 | Chr20: 37.5 | 5.6 | 20.2–43.5 (peak: 31.9) | FP, PP | Arranz et al., Anim Genet, 1998 [34] |
6.3 | 37.8–49.7 (peak: 43.8) | PP | Ashwell et al., J Dairy Sci, 2004 [35] | |||
0.2 | Peak: 37.7 | FP, PP | Zhang et al., Genetics, 1998 [36] | |||
5.2 | 15.5–68.0 (peak: 42.7) | PP | Bennewitz et al., Genetics, 2004 [37] | |||
TRIB3 | 61176217–61187210 | Chr13: 75.8 | 5.2 | Peak: 81.0 | PP | Bagnato et al., J Dairy Sci, 2008 [33] |
5.0 | Peak: 80.8 | FP, PP | Pimentel et al., Anim Genet, 2011 [38] | |||
SESN2 | 125698159–125714128 | Chr2: 116.2 | 14.6 | Peak: 101.6 | FP, PP | Pimentel et al., Anim Genet, 2011 [38] |
HSPD1 | 86438978–86449372 | Chr2: 81.0 | 6.5 | Peak: 74.5 | PP | Bagnato et al., J Dairy Sci, 2008 [33] |
NR4A1 | 27977006–27992869 | Chr5: 32.5 | 12.1 | 29.4–45.5 (peak: 44.6) | PP | Bennewitz et al., Genet Sel Evol, 2003 [39] |
SAA1 | 26693328–26696498 | Chr29: 35.8 | 11.6 | Peak: 24.2 | PP | Bagnato et al., J Dairy Sci, 2008 [33] |
RPL23A | 21526905–21574655 | Chr11:27.8 | 5.8 | Peak: 33.6 | FP | Ashwell et al., J Dairy Sci, 1998 [40] |
8.4 | Peak: 19.4 | PP | Bagnato et al., J Dairy Sci, 2008 [33] | |||
VEGFA | 17255946–17269998 | Chr23: 25.8 | 2.5 | 20.7–41.9 (peak: 28.3) | PP | Viitala et al., J Dairy Sci, 2003 [41] |
2.5 | 14.8–42.9 (peak: 28.3) | PP | Elo et al., Mamm Genome, 1999 [42] | |||
KRT24 | 41557544–41561796 | Chr19: 66.1 | 4.1 | Peak: 70.2. | PP | Bagnato et al., J Dairy Sci, 2008 [33] |
2.2 | Peak: 63.9 | PP | Mosig et al., Genetics, 2001 [43] | |||
4.0 | Peak: 62.1 | PP | Bennewitz et al., Genetics, 2004 [37] | |||
0.8 | 64.5–69.8 (peak: 66.9) | FP | Bennewitz et al., Genet Sel Evol, 2003 [39] | |||
CDKN1A | 10560498–10568780 | Chr23: 16.1 | 12.4 | 14.8–42.9 (peak: 28.5) | PP | Elo et al., Mamm Genome, 1999 [42] |
BoLA-DQB | 25375269–25388620 | Chr23: 38.2 | 9.9 | 14.8–42.9 (peak: 28.3) | PP | Elo et al., Mamm Genome, 1999 [42] |
9.9 | 20.7–41.9 (peak: 28.3) | PP | Viitala et al., J Dairy Sci, 2003 [41] | |||
4.7 | Peak: 42.9 | PP | Bagnato et al., J Dairy Sci, 2008 [33] | |||
PTHLH | 82246521–82258858 | Chr5: 90.7 |  | 76.2–103.1 | PP | Schrooten et al., J Dairy Sci, 2004 [44] |
1.1 | 5.3–104.9 (peak: 89.6) | FP | Bennewitz et al., Genetics, 2004 [37] | |||
11.6 | 34.1–108.3 (peak: 102.3) | PP | Bennewitz et al., Genetics, 2004 [37] | |||
5.2 | 80.1–90.8 (peak: 85.5) | FP | Ashwell et al., J Dairy Sci, 2004 [35] | |||
H4 | 31665561–31667068 | Chr23: 46.8 | 3.9 | Peak: 42.9 | PP | Bagnato et al., J Dairy Sci, 2008 [33] |
DDIT3 | 56285007–56307931 | Chr5: 61.2 | 28.4 | 6.9–102.6 (peak: 89.6) | FP | Bennewitz et al., Genetics, 2004 [37] |
|  | 32.3–69.7 | PP | Schrooten et al., J Dairy Sci, 2004 [44] | |||
M-SAA3.2 | 26755567–26759547 | Chr29: 37.8 | 13.6 | Peak: 24.2 | PP | Bagnato et al., J Dairy Sci, 2008 [33] |
HIST1H2AC | 31579046–31589230 | Chr23: 46.7 | 3.8 | Peak: 42.9 | PP | Bagnato et al., J Dairy Sci, 2008 [33] |