Possible regulatory sub-network involving Nfib , Nfia and Nr3c1 . A flat head on an edge indicates a repressive effect. The connector labeled 5 indicates cooperative activation by both Nfib and Nr3c1. Evidence for each numbered edge is given in the main text. The 52 activated genes are 2-fold over-expressed in the wildtypes compared to Nfib-KO and Nfib-KO, with a q-value ≤0.05.