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Table 1 Examples of gene ontology terms commonly associated with virulence identified in QPX transcriptome; F: molecular function, P: biological process

From: Characterization of the transcriptome and temperature-induced differential gene expression in QPX, the thraustochytrid parasite of hard clams

Gene Ontology term

GO category

GO level

GO ID

Seqs no.

Degradation of biopolymers hydrolase activity

  

Hydrolase activity

F

3

GO:0016787

777

  Nuclease activity

F

5

GO:0004518

29

  Phosphatase activity

F

6

GO:0016791

27

  Lipase activity

F

5

GO:0016298

9

  Phospholipase activity

F

6

GO:0004620

4

  Chitinase activity

F

6

GO:0004568

3

  Glucosidase activity

F

6

GO:0015926

2

  Amylase activity

F

6

GO:0016160

1

  Galactosidase activity

F

6

GO:0015925

1

Peptidase activity

F

4

GO:0008233

203

  Metallopeptidase activity

F

6

GO:0008237

47

  Serine-type peptidase activity

F

5

GO:0008236

45

  Cysteine-type peptidase activity

F

6

GO:0008234

35

  Metalloendopeptidase activity

F

7

GO:0004222

30

  Aspartic-type endopeptidase activity

F

7

GO:0004190

10

  Threonine-type peptidase activity

F

6

GO:0070003

7

  Peptidase inhibitor activity

F

4

GO:0030414

9

Cell homeostasis and protection against oxidative stress

  

Antioxidant activity

F

2

GO:0016209

17

  Peroxidase activity

F

3

GO:0004601

10

  Superoxide metabolic process

P

5

GO:0006801

5

  Catalase activity

F

4

GO:0004096

4

  Thioredoxin-disulfide reductase activity

F

3

GO:0004791

2

  Peroxiredoxin activity

F

5

GO:0051920

2

  Thioredoxin peroxidase activity

F

4

GO:0008379

1

  Glutathione peroxidase activity

F

4

GO:0004602

1

Secretion and polysaccharide production

  

  Polysaccharide metabolic process

P

4

GO:0005976

21

  Polysaccharide biosynthetic process

P

6

GO:0000271

13

  Lipopolysaccharide biosynthetic process

P

6

GO:0009103

3

  Extracellular polysaccharide metabolic process

P

6

GO:0046379

2

  Secretion

P

5

GO:0046903

8

  Exocytosis

P

6

GO:0006887

4

  Vesicle docking involved in exocytosis

P

5

GO:0006904

3

  Vesicle-mediated transport

P

5

GO:0016192

38

Adhesion and recognition

  

  Cell adhesion

P

3

GO:0007155

4

  Receptor activity

F

4

GO:0004872

34

  G-protein coupled receptor protein signaling pathway

P

5

GO:0007186

18

  Cell communication

P

3

GO:0007154

13