Model | AUC | 95% CI | Asy. Sig. of Model | Δ AUC | % Δ AUC | pΔ AUC |
---|---|---|---|---|---|---|
Overweight: n = 1443 (61.4%) | Â | Â | Â | |||
1. Covariates | 0.679 | [0.657,0.700] | 2.68×10−48 | - | - | - |
2. Model 1 + SNP-GRSS | 0.692 | [0.671,0.714] | 9.23×10−56 | 0.013 | 1.91% | 0.001 |
3. Model 2 + CNV | 0.694 | [0.672,0.715] | 1.27×10−56 | 0.002 | 0.28% | 0.372 |
Obese Class I: n = 632 (26.9%) | Â | Â | Â | |||
1. Covariates | 0.621 | [0.594,0.647] | 2.74×10−19 | - | - | - |
2. Model 1 + SNP-GRSS | 0.661 | [0.637,0.686] | 2.77×10−33 | 0.040 | 6.44% | 0.0001 |
3. Model 2 + CNV | 0.662 | [0.638,0.687] | 1.12x10−33 | 0.001 | 0.15% | 0.662 |
Obese Class II: n = 264 (11.2%) | Â | Â | Â | |||
1. Covariates | 0.648 | [0.610,0.685] | 5.22×10−15 | - | - | - |
2. Model 1 + SNP-GRSS | 0.681 | [0.646,0.716] | 6.97×10−22 | 0.033 | 5.09% | 0.025 |
3. Model 2 + CNV | 0.690 | [0.656,0.725] | 5.58×10−24 | 0.009 | 1.32% | 0.123 |
Obese Class III: n = 106, (4.5%) | Â | Â | Â | |||
1. Covariates | 0.711 | [0.660,0.762] | 1.97×1013 | - | - | - |
2. Model 1 + SNP-GRSS | 0.741 | [0.692,0.790] | 4.81×10−17 | 0.030 | 4.22% | 0.029 |
3. Model 2 + CNV | 0.750 | [0.702,0.797] | 3.15×10−18 | 0.009 | 1.21% | 0.152 |