Chr. | Phenotype/QTL | Start | End | QTL length (Mb) | Ensmbl genes in QTL | All genes with cSNVs | NS SNVs | STOP c. SNVs | Splice site SNVs | Indels | New candidate genes | Evidence | Strains | Reference |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | PIA8 | 11 | 19 | 8 | 43 | 3 | 2 | 0 | 0 | 1 | NS SNVs in Ect2l, and ATG4B, indel in ALDH8A1 | F2 | DA.PVG, | [42] |
1 | Eae29 | 15 | 17 | 3 | 18 | 2 | 1 | 0 | 0 | 1 | conserved SNVs in IL22RA2, short indel in ALDH8A1, NS SNV in ATG4B | G10, congene | DA/PVG | |
1 | Eae30 | 129 | 130 | 1 | 7 | 1 | 1 | 0 | 0 | 0 | RGMA, NS SNV in Top1 | G10, congene | DA/PVG | |
1 | CIAA6/EAE6/7 | 156 | 247 | 91 | 1343 | 225 | 136 | 2 | 93 | 12 | stopcodon in Ltbp3 and in Ms4a5 | F2 BC | DA/E3 | [16] |
1 | Eae6 | 176 | 218 | 42 | 764 | 147 | 84 | 1 | 62 | 6 | stopcodon in Ms4a5 | F2 | DA/E3 | [18] |
1 | Eae31 | 185 | 185 | 1 | 6 | 3 | 2 | 0 | 1 | 0 | IL21R 1 cons SNV, splice site in IL4R, NS SNVs in Gtf3c and LOC361646 | G10, congene | DA/PVG | |
1 | Eae7 | 240 | 247 | 7 | 64 | 25 | 16 | 0 | 12 | 1 | indel in Myof, splice site SNV in Znf518a | F2 | DA/E3 | [18] |
4 | PIA2/AIA2 | 32 | 42 | 10 | 28 | 7 | 6 | 0 | 3 | 2 | indel in Dpp6, and frameshift SNV in Tmem106b | F2 BC | DA/BN, E3 | |
4 | Eae24 | 60 | 75 | 15 | 146 | 28 | 21 | 1 | 9 | 0 | stop in an orf in a intron of Dgki | G10, congene | DA/PVG | |
4 | Eae25 | 75 | 83 | 8 | 88 | 22 | 19 | 0 | 6 | 1 | indel in Znf282 (HUB1) | G10, congene | DA/PVG | |
4 | PIA5/CIA3 | 78 | 104 | 26 | 248 | 56 | 45 | 2 | 9 | 2 | 2 Stop in Igk genes | F2 BC congene | DA/BN,E3 | |
4 | Eae26 | 83 | 104 | 21 | 206 | 28 | 24 | 0 | 5 | 2 | indel in Herc6, and RPS7 | G10, congene | DA/PVG | |
4 | Eae27 | 104 | 114 | 10 | 61 | 7 | 6 | 0 | 1 | 0 | NS SNVs in both CD8a and Cd8b | G10,congene | DA/PVG | |
4 | Eae20 | 156 | 161 | 5 | 88 | 24 | 18 | 2 | 8 | 1 | indel in Rad52, stop in Clec4b2, stop in Q6QI20 | G10, congene | DA/PVG | |
4 | PIA7/OIA2/CIA13 | 159 | 160 | 1 | 23 | 8 | 6 | 2 | 2 | 0 | stop in Clec4b2 | F2 congene | DA/E3,PVG | |
4 | Eae21 | 161 | 162 | 1 | 23 | 4 | 2 | 0 | 3 | 0 | splice SNV in Pianp, Zfp384, NS SNV Vwf | G10,congene | DA/PVG | |
4 | Eae22 | 162 | 172 | 10 | 137 | 34 | 27 | 1 | 14 | 1 | Essential splice site SNV in Klrc2, stop Clec2 | G10, BC | DA/PVG | |
5 | CIAA5 | 138 | 172 | 34 | 554 | 113 | 92 | 1 | 27 | 4 | Stop in orf, indel in Nmnat1, Myom3, SZT2 | F2 BC | DA/E3 | |
6 | PIA3/eae9 | 117 | 144 | 31 | 249 | 70 | 55 | 1 | 16 | 6 | stop in F1M0Z7_RAT | F2 congene | DA/E3 | |
7 | PIA13 | 62 | 78 | 16 | 116 | 15 | 12 | 0 | 2 | 1 | indel in Ptdss1 | F2 | DA/E3 | |
8 | PIA14 | 79 | 87 | 8 | 53 | 11 | 8 | 0 | 3 | 0 | splice site in Lrrc1, Ick, Eef1a1 | F2 | DA/E3 | |
10 | Vra4/Eae | 0 | 11 | 11 | 94 | 13 | 11 | 0 | 2 | 0 | no coding SNVs in Ciita | congene | DA/PVG | |
10 | Eae18a | 55 | 67 | 12 | 303 | 67 | 47 | 1 | 20 | 2 | stop in krt18-b, 2 NSC and splice site SNV in Nos2 | G7,G10,congene | DA/PVG | |
10 | Eae18b | 67 | 72 | 5 | 68 | 22 | 12 | 0 | 10 | 2 | CCL11 conserved SNVs | G7,G10,cong. | DA/PVG | |
10 | CIA5A OIA3 PIA10 EAN5 | 95 | 110 | 15 | 214 | 36 | 29 | 0 | 8 | 3 | Cd300 hyper polymorphic regions, indel in Fdxr, Acox1, Tnrc6c | G10 F2 congene | DA/PVG | |
11 | Pia27, RF | 84 | 86 | 2 | 53 | 6 | 4 | 0 | 2 | 1 | Essential splice site in Lac2 | F2 congene | DA/E3 | [51] |
12 | Eae5 | 20 | 24 | 4 | 70 | 16 | 11 | 0 | 5 | 0 | NCF1, CLN4, splice site SNV i Gtfi1 | G7, congene | DA/PVG | |
12 | PIA4/NCF1 | Â | Â | * | Â | Â | 1 | Â | Â | Â | NCF1 NS SNV aa153 | congene | DA/E3 | |
14 | PIA6/EAE10/CIAA7 | 32 | 103 | 71 | 408 | 39 | 25 | 0 | 12 | 3 | NS SNV Tlr10, Igfbp3, indel Aebp1, Apex2 | F2 | DA/E3 | |
15 | Eae19 | 83 | 97 | 14 | 33 | 7 | 7 | 0 | 1 | 0 | Lmo7, Tbc1d4, Mycbp2, Uchl3, Slitrk6 | G7,congene | DA/PVG | |
17 | Eae23a | 36 | 57 | 21 | 180 | 13 | 12 | 0 | 1 | 0 | NS SNVs in Ripk1, Serpinb1a, Gpx6, splice-SNV in Agtr1a | G10, cong. | DA/PVG | |
17 | Eae23b | 57 | 66 | 9 | 49 | 11 | 8 | 1 | 3 | 1 | stop in Prelid1 | G10, cong. | DA/PVG | |
20 | Pia1 | 3 | 5 | 2 | 114 | 50 | 40 | 1 | 16 | 0 | NS SNVs in Ncr3, Lst1, RT1-Ba, Tap2, Psmb8, Tap1, Psmb9, Stop in RT1-CE4 | F2 | DA/E3, PVG DA/LEW,BN | |
20 | Eae1 | 5 | 7 | 2 | 55 | 14 | 8 | 0 | 4 | 3 | NS SNVs in Tapbp, RT1-A2, RT1-A2 frameshift mutation in Grm3 | F2 | DA/E3, PVG DA/LEW,BN | [18] |