Table 4 Genes which were down regulated in small atretic follicles with respect to healthy folliclesâ€
From: Transcriptome profiling of granulosa cells from bovine ovarian follicles during atresia
Gene symbol | Fold change | Gene symbol | Fold change | Gene symbol | Fold change |
|---|---|---|---|---|---|
Cell Cycle | |||||
HAUS4 | 9.7 | CASC5 | 4.1 | FAM83D | 3.4 |
KIFC1 | 7.2 | *PTTG1 | 4.0 | CDCA2 | 3.3 |
TOP2A | 6.3 | BUB1 | 3.9 | KIF23 | 3.3 |
HJURP | 5.6 | SKA3 | 3.9 | CENPF | 3.3 |
CDCA8 | 4.6 | TPX2 | 3.8 | MCM10 | 3.3 |
MDC1 | 4.5 | SGOL1 | 3.8 | CDCA3 | 3.3 |
RAD51AP1 | 4.5 | CDC20 | 3.8 | OIP5 | 3.2 |
CENPE | 4.5 | GINS3 | 3.7 | ASPM | 3.2 |
ANAPC5 | 4.4 | ASF1B | 3.7 | NCAPH | 3.2 |
NUSAP1 | 4.3 | CDC6 | 3.7 | MAD2L1 | 3.1 |
MYO1D | 4.3 | ERCC6L | 3.6 | CKAP2 | 3.1 |
KLC2 | 4.3 | CCNB1 | 3.6 | *CENPA | 3.1 |
BUB1B | 4.2 | PRCC | 3.5 | AURKB | 3.0 |
CNNM2 | 4.2 | CENPN | 3.5 | Â | Â |
Cell Death | |||||
TRIB2 | 6.5 | RIPK3 | 4.8 | Â | Â |
Cell Morphology | |||||
CKAP2L | 4.7 | SRGN | 4.0 | MAPT | 3.3 |
PLP1 | 4.6 | HMMR | 3.8 | PRC1 | 3.3 |
JAKMIP1 | 4.6 | RSPH9 | 3.7 | TNNC1 | 3.2 |
TMEM138 | 4.5 | SYNPO | 3.6 | PHACTR1 | 3.1 |
ECT2 | 4.2 | LEMD2 | 3.5 | MYO5C | 3.0 |
TMEM216 | 4.0 | CDH26 | 3.5 | Â | Â |
Cytokines, Hormones and Receptors | |||||
FGFR2 | 8.4 | INHA | 3.8 | CCR3 | 3.2 |
F2RL2 | 5.9 | ADRA1A | 3.7 | CHRM4 | 3.2 |
VEGFA | 5.8 | IL7 | 3.6 | P2RY10 | 3.2 |
RHO | 5.8 | CD5 | 3.6 | NR5A1 | 3.2 |
IL17RE | 5.5 | GPR128 | 3.6 | OPN1LW | 3.2 |
LTA | 4.8 | GPR61 | 3.6 | AHR | 3.2 |
IL18R1 | 4.6 | GPR77 | 3.5 | IL20RA | 3.2 |
FSHR | 4.4 | FGF10 | 3.4 | HTR1D | 3.2 |
HTR2A | 4.4 | CCL11 | 3.4 | FGFBP1 | 3.1 |
AMH | 4.2 | OPCML | 3.4 | TSHB | 3.1 |
GPRC5A | 4.2 | CCL25 | 3.4 | ASGR1 | 3.1 |
OPRM1 | 4.2 | CCL28 | 3.4 | HEG1 | 3.1 |
INHBA | 4.2 | FIGF | 3.4 | IL1A | 3.1 |
NTRK3 | 4.1 | CD72 | 3.3 | IGF1 | 3.1 |
FST | 4.0 | ABP1 | 3.3 | CASR | 3.0 |
FSHB | 4.0 | EDNRA | 3.3 | GMFG | 3.0 |
IL21 | 4.0 | ITGB3 | 3.2 | HTR4 | 3.0 |
BMP15 | 3.8 | NGFR | 3.2 | Â | Â |
Directional Cell Growth | |||||
FAT1 | 3.6 | Â | Â | Â | Â |
Extracellular Matrix and Synthesis | |||||
LAMC2 | 6.4 | COL6A6 | 3.7 | COL10A1 | 3.5 |
EPYC | 4.3 | TRAM2 | 3.6 | *AMELX//AMELY | 3.3 |
Intercellular and Cell to Matrix Adhesion | |||||
MUC15 | 5.7 | CLDN6 | 3.8 | DSG1 | 3.1 |
PRELP | 4.5 | CD33 | 3.5 | PECAM1 | 3.1 |
*MCAM | 4.0 | SMAGP | 3.5 | EPDR1 | 3.1 |
*GLYCAM1 | 3.9 | *BOLA-DQ2 | 3.3 | CLEC4E | 3.0 |
SELL | 3.9 | CD96 | 3.2 | Â | Â |
Ion Transport | |||||
TTYH1 | 4.8 | KCNE1 | 3.4 | SLC25A34 | 3.1 |
FXYD7 | 4.3 | P2RX5 | 3.2 | CACNA1D | 3.1 |
KCNJ15 | 3.5 | TRPM6 | 3.2 | *KCNIP2 | 3.0 |
Protein Trafficking | |||||
INSIG1 | 3.8 | VPS52 | 3.2 | Â | Â |
Proteolysis or Inhibition | |||||
*PTI | 58.8 | TROAP | 3.5 | DBC1 | 3.2 |
CPXM2 | 5.2 | MMP7 | 3.4 | TASP1 | 3.2 |
TFPI | 5.1 | ACE2 | 3.3 | PGA5 | 3.1 |
PRSS22 | 4.4 | CPB1 | 3.3 | SERPINI2 | 3.1 |
CUL7 | 4.3 | SPPL2B | 3.2 | MMP3 | 3.0 |
KLK4 | 4.1 | SPAG5 | 3.2 | TRIM8 | 3.0 |
USP28 | 3.8 | Â | Â | Â | Â |
RNA Processing | |||||
DCP1A | 3.6 | U2SURP | 3.0 | Â | Â |
Transcription Regulation | |||||
ZFHX3 | 6.3 | HAND1 | 3.8 | BCORL1 | 3.2 |
HOXB2 | 4.6 | NFE2L2 | 3.6 | NCOA6 | 3.2 |
ZNF385A | 4.5 | SP100 | 3.6 | EHMT2 | 3.2 |
CCNT1 | 4.5 | UHRF1 | 3.5 | CC2D1B | 3.2 |
SRCAP | 4.3 | BCOR | 3.5 | IRF2BP1 | 3.2 |
LDB1 | 4.2 | RFX5 | 3.4 | NSD1 | 3.1 |
POLR3D | 4.0 | NOTCH4 | 3.4 | TFAP2A | 3.1 |
ELK1 | 4.0 | ASB12 | 3.3 | ZBTB4 | 3.1 |
VSX1 | 4.0 | NFIA | 3.3 | POU1F1 | 3.1 |
VGLL1 | 3.8 | HOXD9 | 3.2 | ZNF274 | 3.0 |
Translation Regulation | |||||
YBX2 | 4.9 | EEFSEC | 3.3 | EEF1A1 | 3.1 |
NARS | 3.3 | Â | Â | Â | Â |
Transport | |||||
AQP1 | 7.0 | SLC12A8 | 4.0 | SLC8A1 | 3.4 |
TRPA1 | 6.1 | SLC5A9 | 4.0 | EPB42 | 3.4 |
*ATP10A | 6.1 | PDYN | 4.0 | SYNGR3 | 3.3 |
TNPO1 | 6.0 | SLC24A1 | 4.0 | SLC6A9 | 3.2 |
ALB | 5.7 | RHBG | 4.0 | AP4B1 | 3.2 |
SLC27A3 | 5.5 | ATP13A2 | 3.8 | GOSR1 | 3.2 |
SLCO2B1 | 5.1 | KIF20A | 3.6 | ATP4A | 3.2 |
APOB | 5.0 | STRA6 | 3.6 | PLLP | 3.2 |
MAL2 | 4.6 | CLDN16 | 3.5 | FLVCR2 | 3.1 |
SLC4A2 | 4.5 | SLC7A1 | 3.5 | SLC37A2 | 3.0 |
ATP2B4 | 4.4 | GC | 3.4 | SLC13A2 | 3.0 |
ABCD1 | 4.2 | ENSA | 3.4 | SLC38A11 | 3.0 |
SLC16A3 | 4.1 | Â | Â | Â | Â |
Other Enzymes | |||||
CYP19A1 | 19.8 | CYP4F2 | 4.2 | PNLIP | 3.4 |
AOAH | 15.1 | PDE4D | 4.1 | PDE6G | 3.3 |
*PDK4 | 9.7 | GPT | 4.1 | TRNAU1AP | 3.3 |
NOS2 | 8.8 | PDP2 | 3.9 | ALDH1L2 | 3.3 |
ISG20 | 8.4 | DBT | 3.9 | PJA2 | 3.3 |
ALG3 | 7.8 | LPO | 3.9 | WDR46 | 3.3 |
CHST8 | 7.0 | ALOX12B | 3.8 | IPMK | 3.2 |
HMGCS1 | 6.9 | METTL7B | 3.7 | ST6GAL1 | 3.2 |
GCLC | 6.9 | *IGL@ | 3.7 | ALG5 | 3.2 |
CA14 | 6.8 | *IGHG | 3.7 | CA5B | 3.2 |
UGT2B17 | 6.5 | ETNK2 | 3.6 | ACAD10 | 3.2 |
AKR1C3 | 5.9 | PIPOX | 3.6 | DIO1 | 3.2 |
GYLTL1B | 5.7 | RNF168 | 3.6 | ACSM1 | 3.1 |
SCD | 5.6 | LHPP | 3.6 | GSTM4 | 3.1 |
GPX3 | 5.4 | CYP21A2 | 3.6 | RSAD2 | 3.1 |
CYP2C19 | 5.2 | NQO1 | 3.6 | ACSM2A | 3.1 |
GPX2 | 5.0 | METTL21B | 3.5 | SH3GL2 | 3.1 |
HSD17B1 | 4.8 | GCNT1 | 3.5 | SEPT4 | 3.1 |
*FHL3 | 4.7 | LPPR2 | 3.5 | UBE2C | 3.1 |
LPL | 4.6 | BCAT1 | 3.5 | RBBP8 | 3.1 |
PLA2G1B | 4.5 | BBOX1 | 3.5 | B3GNT3 | 3.1 |
PPP3CC | 4.5 | PNLIPRP2 | 3.5 | DUSP14 | 3.0 |
PDE6A | 4.4 | METTL2A | 3.4 | GNA14 | 3.0 |
FMO2 | 4.4 | P4HA2 | 3.4 | CPS1 | 3.0 |
TYRP1 | 4.3 | GALNT13 | 3.4 | Â | Â |
CMBL | 4.2 | DCT | 3.4 | Â | Â |
Other Signalling | |||||
IHH | 7.1 | MAP4K1 | 4.0 | LAT | 3.3 |
HLA-A | 6.2 | RIC3 | 3.8 | PILRA | 3.3 |
TBKBP1 | 6.2 | CD84 | 3.8 | GPSM3 | 3.2 |
*HSPA1A | 5.7 | SHCBP1 | 3.6 | DNAJB1 | 3.1 |
TESPA1 | 5.4 | GUCA1A | 3.6 | KIR2DL5A | 3.1 |
JAK3 | 5.1 | MTUS1 | 3.4 | PEX11B | 3.1 |
GUCY2F | 4.6 | DOK2 | 3.4 | UPK1A | 3.1 |
SKAP1 | 4.5 | RPS6KA4 | 3.3 | LY6G6C | 3.1 |
RASGRP4 | 4.2 | RGS3 | 3.3 | FIGNL1 | 3.0 |
BCL9 | 4.0 | Â | Â | Â | Â |
Other | |||||
CSN2 | 17.7 | EMID1 | 4.3 | GIMAP7 | 3.5 |
MZB1 | 10.1 | CYLC1 | 4.3 | GUCA2A | 3.4 |
STAC3 | 6.8 | CCDC159 | 4.3 | PLEKHF2 | 3.4 |
CCDC3 | 6.3 | C21orf62 | 4.2 | IFI44L | 3.4 |
C9orf152 | 5.9 | C1orf170 | 4.2 | ODZ3 | 3.4 |
AGR2 | 5.8 | APOBEC4 | 4.2 | MICA | 3.3 |
STAC | 5.6 | VWA8 | 4.1 | TMEM139 | 3.3 |
EFHD1 | 5.5 | PEAR1 | 4.1 | UBN2 | 3.3 |
MTHFSD | 5.4 | MPDZ | 4.0 | C6orf47 | 3.3 |
NXPH2 | 5.4 | IFIT2 | 4.0 | Btnl1 | 3.3 |
SPEF1 | 5.3 | ELMOD3 | 4.0 | CXorf64 | 3.3 |
CRISPLD2 | 5.2 | PLEK | 4.0 | DENND2D | 3.3 |
KLHL29 | 5.2 | SOWAHA | 3.9 | CHAC1 | 3.3 |
MEX3C | 5.0 | GCA | 3.8 | BIRC5 | 3.2 |
CAMP | 4.7 | LY9 | 3.8 | CAPSL | 3.2 |
KIAA0101 | 4.6 | CCDC132 | 3.7 | *RSPH10B | 3.2 |
HRG | 4.6 | CRP | 3.6 | ANKRD17 | 3.1 |
KLHL33 | 4.6 | C16orf53 | 3.6 | *RNFT1 | 3.1 |
CEP85 | 4.5 | HYOU1 | 3.6 | HYDIN | 3.1 |
PTGFRN | 4.5 | RASGEF1A | 3.6 | ASPHD1 | 3.1 |
TMIGD2 | 4.5 | PIP | 3.6 | CCDC97 | 3.0 |
C6 | 4.4 | OLFML1 | 3.5 | CCDC43 | 3.0 |
WDR76 | 4.4 | FAM178A | 3.5 | *PA1 | 3.0 |
MOB3B | 4.4 | TAGLN3 | 3.2 | MLKL | 3.0 |
RBL2 | 3.8 | TMED6 | 3.2 | WDR87 | 3.0 |