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Table 4 LSPPgenes depleted in vivo (as defined in [13])

From: Disruption of Mycobacterium avium subsp. paratuberculosis-specific genes impairs in vivo fitness

LSPP Region description Average ratio Standard deviation Predicted function
4 MAP0856c (MAPK_2912) 0.0843 0.0720 H.P.
4 MAP0862 (MAPK_2906) 0.0189 0.0378 H.P.
4 MAP0865 (MAPK_2903) 0.0000 0.0000 Cell division protein
11 MAP2148 (MAPK_1620) 0.0653 0.0640 Phage integrase
11 MAP2150 (MAPK_1618) 0.0827 0.0087 Transposase
11 MAP2154c (MAPK_1614) 0.1038 0.0153 H.P.
11 MAP2157 (MAPK_1611) 0.1216 0.0910 Transposase
11 MAP2158 (MAPK_1610) 0.1255 0.0333 H.P.
12 MAP2185c (MAPK_1583) 0.1410 0.1087 Amidohydrolase
12 MAP2194 (MAPK_1574) 0.0787 0.0703 Mce family protein
14 MAP3731c (MAPK_0037) 0.0302 0.0509 ABC transporter ATP-binding Protein
14 MAP3733c (MAPK_0035) 0.1041 0.0890 H.P.
14 MAP3735c (MAPK_0033) 0.0557 0.0533 ABC transporter ATP-binding Protein
14 MAP3741 (MAPK_0027) 0.0039 0.0005 H.P.
14 MAP3742 (MAPK_0026) 0.0265 0.0178 H.P.
14 MAP3745 (MAPK_0023) 0.0104 0.0154 H.P.
14 MAP3750 (MAPK_0018) 0.0111 0.0057 MmpS1 family protein
14 MAP3751 (MAPK_0017) 0.0746 0.0970 transmembrane transport protein, MmpL4_5
14 MAP3757c (MAPK_0011) 0.0923 0.0679 H.P.
14 MAP3759c (MAPK_3761) 0.0836 0.0106 Tranposase
14 MAP3760c (n. a.) 0.0400 0.0065 H.P.
14 MAP3763c (MAPK_3765) 0.0372 0.0267 PapA2_3
14 MAP3764c (MAPK_3766) 0.1181 0.1928 Pks2
15 MAP3776c (MAPK_3778) 0.1353 0.2561 ABC transporter periplasmic solute binding protein
16 MAP3816 (MAPK_3818) 0.0701 0.0757 Phage integrase
16 MAP3817c (MAPK_3819) 0.1251 0.0114 H.P.
  1. LSPP genes depleted in vivo with an average ratio of less than 0.1 × median (0.153). Gene annotation by Li et al shown in second column with Wynne et al annotation in brackets. H.P. = Hypothetical protein, Mce = Mammalian cell entry, Mmp = Membrane protein, Pap = Polyketide associated protein, Pks = Polyketide synthase, n. a. = not annotated.