Skip to main content

Table 3 Pathway of RNA-seq involved in immunity and inflammation responses after infection for four weeks

From: De novo assembly and transcriptome characterization: novel insights into the natural resistance mechanisms of Microtus fortis against Schistosoma japonicum

Pathway DEGs with pathway annotation All genes with pathway annotation
  1st w (700) 2nd w (946) 3rd w (665) 4th w (432) 1st w 2nd w 3rd w 4th w
Jak-STAT signaling 15 (2.14%) 22 (2.33%) 13 (1.95%) 5 (1.16%) 577 (1.51%) 577 (1.51%) 577 (1.51%) 577 (1.51%)
MAPK signaling 26 (3.71%) 29 (3.07%) 16 (2.41%) 9 (2.08%) 1058 (2.76%) 1058 (2.76%) 1058 (2.76%) 1058 (2.76%)
apoptosis 9 (1.29%) 12 (1.27%) 5 (0.75%) 3 (0.69%) 373 (0.97%) 373 (0.97%) 373 (0.97%) 373 (0.97%)
NF-kappa B 23 (3.29%) 37 (3.91%) 11 (1.65%) 8 (1.85%) 477 (1.25%) 477 (1.25%) 477 (1.25%) 477 (1.25%)
Toll-like receptor signaling 22 (3.14%) 22 (2.33%) 15 (2.26%) 4 (0.93%) 405 (1.06%) 405 (1.06%) 405 (1.06%) 405 (1.06%)
Natural killer cell mediated cytotoxicity 36 (5.14%) 43 (4.55%) 16 (2.41%) 8 (1.85%) 532 (1.39%) 532 (1.39%) 532 (1.39%) 532 (1.39%)
Fc gamma R-mediated phagocytosis 33 (4.71%) 41 (4.33%) 20 (3.01%) 16 (3.7%) 570 (1.49%) 570 (1.49%) 570 (1.49%) 570 (1.49%)
Complement and coagulation cascades 25 (3.57%) 28 (2.96%) 20 (3.01%) 19 (4.4%) 459 (1.2%) 459 (1.2%) 459 (1.2%) 459 (1.2%)
B cell receptor signaling pathway 22 (3.14%) 35 (3.7%) 15 (2.26%) 11 (2.55%) 424 (1.11%) 424 (1.11%) 424 (1.11%) 424 (1.11%)
T cell receptor signaling pathway 15 (2.14%) 23 (2.43%) 10 (1.5%) 11 (2.55%) 462 (1.21%) 462 (1.21%) 462 (1.21%) 462 (1.21%)
Cytokine-cytokine receptor interaction 21 (3%) 29 (3.07%) 22 (3.31%) 5 (1.16%) 738 (1.93%) 738 (1.93%) 738 (1.93%) 738 (1.93%)
RIG-I-like receptor signaling pathway 8 (1.14%) 10 (1.06%) 6 (0.9%) 2 (0.46%) 245 (0.64%) 245 (0.64%) 245 (0.64%) 245 (0.64%)
NOD-like receptor signaling pathway 8 (1.14%) 9 (0.95%) 6 (0.9%) 2 (0.46%) 343 (0.9%) 343 (0.9%) 343 (0.9%) 343 (0.9%)
TGF-beta signaling pathway 2 (0.29%) 12 (1.27%) 6 (0.9%) 1 (0.23%) 344 (0.9%) 344 (0.9%) 344 (0.9%) 344 (0.9%)
Wnt signaling pathway 5 (0.71%) 12 (1.27%) 3 (0.45%) 3 (0.69%) 630 (1.64%) 630 (1.64%) 630 (1.64%) 630 (1.64%)
Ubiquitin mediated proteolysis 5 (0.71%) 11 (1.16%) 9 (1.35%) 1 (0.23%) 668 (1.74%) 668 (1.74%) 668 (1.74%) 668 (1.74%)
  1. Note: 1st w, first week after infection; 2nd w, second week after infection; 3rd w, third week after infection; 4th w, fourth week after infection.