Figure 6

P-value heatmaps for immunity-related categories. Immune genes were separated into the categories “recognition”, “extracellular signaling”, “intracellular signaling” and “execution” according to [14]. P-values are based on the overrepresentation analysis of A) immune gene sets in significantly upregulated genes, B) immune gene sets in significantly downregulated genes, C) “intracellular signaling” gene sets in significantly upregulated genes, D) “intracellular signaling” gene sets in significantly downregulated genes, E) “execution” gene sets in significantly upregulated genes and F) “execution” gene sets in significantly downregulated genes for every of the twelve pairwise differential expression analyses; an asterisk indicates p<0.05 (Fisher’s Exact Test; p-value corrected for multiple testing according to the Benjamini Hochberg procedure). Significant up- and downregulation is based on Cufflinks analyses with the default q-value cutoff of 0.05 [60].