Table 2 KEGG pathways enriched for targets of the 19 up-regulated miRNAs in the backfat tissues of castrated pigs
Signaling pathway term | Count | P-value | Benjamini |
|---|---|---|---|
Adherens junction | 37 | 3.40 E-09 | 3.00 E-07 |
Axon guidance | 51 | 9.50 E-09 | 5.50 E-07 |
MAPK signaling pathway | 85 | 1.60 E-08 | 6.70 E-07 |
Wnt signaling pathway | 54 | 1.70 E-07 | 5.90 E-06 |
Focal adhesion | 66 | 2.30 E-07 | 6.80 E-06 |
Regulation of actin cytoskeleton | 69 | 3.20 E-07 | 7.80 E-06 |
Neurotrophin signaling pathway | 46 | 5.00 E-07 | 1.10 E-05 |
TGF-beta signaling pathway | 35 | 1.90 E-06 | 3.20 E-05 |
Endocytosis | 59 | 2.70 E-06 | 4.30 E-05 |
Long-term potentiation | 28 | 1.50 E-05 | 2.20 E-04 |
Ubiquitin mediated proteolysis | 44 | 6.00 E-05 | 7.40 E-04 |
ErbB signaling pathway | 31 | 1.20 E-04 | 1.20 E-03 |
Tight junction | 42 | 1.70 E-04 | 1.50 E-03 |
Type II diabetes mellitus | 18 | 2.00 E-03 | 1.50 E-02 |
Hedgehog signaling pathway | 19 | 6.30 E-03 | 3.80 E-02 |
mTOR signaling pathway | 18 | 6.50 E-03 | 3.80 E-02 |
Fc gamma R-mediated phagocytosis | 28 | 6.50 E-03 | 3.70 E-02 |
Gap junction | 26 | 1.00 E-02 | 5.50 E-02 |
Insulin signaling pathway | 36 | 1.00 E-02 | 5.50 E-02 |
Aldosterone-regulated sodium reabsorption | 14 | 2.10 E-02 | 1.00 E-01 |
Chemokine signaling pathway | 45 | 2.50 E-02 | 1.20 E-01 |
Cell cycle | 32 | 2.80 E-02 | 1.20 E-01 |
Vascular smooth muscle contraction | 29 | 3.20 E-02 | 1.40 E-01 |
Calcium signaling pathway | 42 | 3.50 E-02 | 1.40 E-01 |
Long-term depression | 19 | 5.30 E-02 | 2.00 E-01 |
T cell receptor signaling pathway | 27 | 5.80 E-02 | 2.10 E-01 |
Leukocyte transendothelial migration | 29 | 5.90 E-02 | 2.10 E-01 |
GnRH signaling pathway | 24 | 9.00 E-02 | 2.80 E-01 |
Phosphatidylinositol signaling system | 19 | 9.40 E-02 | 2.90 E-01 |