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Figure 8 | BMC Genomics

Figure 8

From: Next-generation sequencing of small RNAs from inner ear sensory epithelium identifies microRNAs and defines regulatory pathways

Figure 8

A newly identified miRNA-target regulatory pathway in the inner ear. A suggested pathway for miR-6715-3p and Arhgap12, whereby miR-6715-3p down-regulates expression of Arhgap12, which in turn blocks the hydrolysis of Rac1 (Ras-Related C3 Botulinum Toxin Substrate 1) GTPase. This may result in increased cell adhesion, actin reorganization and inner ear morphogenesis.

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BMC Genomics

ISSN: 1471-2164

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