Dendrogram of 223 sequences of class-II basidiomycete heme peroxidases (AA2) showing the position of nine sequences from the P. cinnabarinus genome (orange background). Evolutionary analysis was performed with MEGA5 using Poisson distances and an unweighted pair group method with arithmetic mean clustering. The cytochrome c peroxidase from P. ostreatus, monokaryon PC9, was used to root the tree (http://phylobench.vital-it.ch/raxml-bb/). The dendogram was used to illustrate the clustering of sequences (clusters A to E). Clusters with no P. cinnabarinus sequences included were collapsed. Most of the sequences were obtained from the analysis of fungal genome sequences deposited at the US Department of Energy Joint Genome Institute (JGI), with the rest collected from GenBank . Fungal abbreviations are as follows: BJEAD, Bjerkandera adusta (JGI); DICSQ, Dichomitus squalens (JGI); FOMME, Fomitiporia mediterranea (JGI); GANSP, Ganoderma sp. (JGI); HETAN, Heterobasidion annosum (JGI); PHLBR, Phlebia brevispora (JGI); PYCCI, Pycnoporus cinnabarinus; STEHI, Stereum hirsutum (JGI); TRACE, Trametopsis cervina; and TRAVE, Trametes versicolor (JGI). Other fungal species with peroxidase sequences included in the collapsed clusters are: Agaricus bisporus (JGI), Auricularia delicata (JGI), Bjerkandera sp (JGI), Ceriporiopsis rivulosa, Coprinellus disseminatus, Coprinopsis cinerea (JGI), Fomitopsis pinicola (JGI), Ganoderma applanatum, Ganoderma australe, Ganoderma formosanum, Ganoderma lucidum, Gelatoporia subvermispora (JGI), basidiomycete IZU-154, Laccaria bicolor (JGI), Lentinula edodes, Phanerochaete chrysosporium (JGI), Phanerochaete sordida, Phlebia radiata, Pleurotus eryngii, Pleurotus ostreatus (JGI), Pleurotus pulmonarius, Pleurotus sapidus, Punctularia strigosozonata (JGI), Rhodonia placenta (JGI), Spongipellis sp., Taiwanofungus camphoratus, Wolfiporia cocos (JGI).