Figure 9

Three nucleosome occupancy clusters around proximal activator and repressor binding sites. (A) Three nucleosome occupancy clusters for proximal activator binding sites in the GM12878 cell line. The first three panels were traditional aggregate plots of the nucleosome occupancy signals for all proximal activator sites, sites with high nucleosome signals and sites with low nucleosome signals. The rest of the panels exhibited three nucleosome occupancy patterns averaged over the proximal activator sites in each of the clusters. (B) Three nucleosome occupancy clusters for proximal activator binding sites in the K562 cell line. (C, D) Three nucleosome occupancy clusters for proximal repressor binding sites in GM12878 and K562 cells.