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Figure 5 | BMC Genomics

Figure 5

From: L-carnitine and PPARα-agonist fenofibrate are involved in the regulation of Carnitine Acetyltransferase (CrAT) mRNA levels in murine liver cells

Figure 5

Protein complexes binding to RXRα binding site at the CrAT promoter. (A) EMSA. Nuclear extracts from TIB-73 cells supplemented with increasing concentrations of L-carnitine were incubated with γ-32P-labeled oligonucleotides representing the RXRα-binding site with anti-PPARα as indicated. (B) Histogramm of the denstitometrical scan of the EMSA presented in A. Values are mean ± SD, n = 3, ***p < 0.001 and *p < 0.05 vs. Corresponding supplementation levels are indicated with parentheses and asterisks on top to indicate the statistical significance of the p-values.

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