Various strategies have been developed for visualizing genetic sequences. For example, the notation proposed by Cowin et al. uses dots arranged like notes on a music stave to display genetic data (A). Jarvius and Landegren’s DNA Skyline notation represents nucleotides as differently sized blocks (B). Finally, Schneider and Stephens’ Sequence Logo uses stacked, variably-sized IUPAC characters to display genetic variation in sequence alignments (C).