Figure 6

Differential expression of miRNAs in Anopheles females 3 h after regular and infectious blood feeding. (A) Fold-changes in miRNA expression are shown as a ratio of blood-fed to sugar-fed mosquitoes (p > 0.05). (B) Multiple RNA sequence alignment for mouse and human homologs of Anopheles miR-92a (miRBase v19). Sequence compilations of miR-92a mature sequence with the 3’-end variation in the mosquito libraries as indicated. (C) Sequence read abundance corresponding to two abundant classes of aga-miR-92a and mmu-miR-92a in sugar and blood-fed mosquitoes are as indicated. (D) Differentially expressed miRNAs in P. berghei infected mosquitoes; the fold-changes in miRNA expression levels are shown as a ratio of infected to non-infected blood-fed mosquito samples (p > 0.05).