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Table 4 Enzymes identified in the cucurbitacin E and I pathway and their change in gene expression

From: Identification of cucurbitacins and assembly of a draft genome for Aquilaria agallocha

Enzyme Enzyme 0.5 mM/0 mM
Name Commission Ratio
1-deoxy-D-xylulose-5-phosphate synthase (DXPS) 2.2.1.7 7.1334
1-deoxy-D-xylulose-5-phosphate reductoisomerase (DXR) 1.1.1.267 1.2901
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase (MCT) 2.7.7.60 0.4569
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase (CMK) 2.7.1.148 1.8742
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase (MCS) 4.6.1.12 0.8282
4-hydroxy-3-methylbut-2-enyl diphosphate synthase (HDS) 1.17.7.1 5.4502
4-hydroxy-3-methylbut-2-enyl diphosphate reductase (HDR/IDS) 1.17.1.2 5.9418
acetyl-CoA acetyltransferase (AACT) 2.3.1.9 1.5835
hydroxymethylglutaryl-CoA synthase (HMGS) 2.3.3.10 3.0714
3-hydroxy-3-methylglutaryl-CoA reductase (HMGR) 1.1.1.34 20.4453
mevalonate kinase (MK) 2.7.1.36 2.2961
phosphomevalonate kinase (PMK) 2.7.4.2 1.6881
diphosphomevalonate decarboxylase (MVD) 4.1.1.33 2.3948
isopentenyl-diphosphate delta-isomerase (IPI) 5.3.3.2 1.9775
geranylgeranyl pyrophosphate synthetase (GGPS) 2.5.1.29 3.1042
squalene synthetase (SQS) 2.5.1.21 2.0913
cycloartenol synthase (CAS) 5.4.99.8 1.5239
squalene monooxygenase (SE) 1.14.13.132 1.5357
vascular plant one-zinc-finger transcription factor (VOZ)   1.3396