Figure 1
From: Chromosome-breakage genomic instability and chromothripsis in breast cancer
Flow sorting profiles of tumor specimens and copy number patterns associated with different tumor subpopulations. Flow sorting profiles (A-C) and copy number patterns (genome-wide views) identified with the ADM-2 algorithm (D-F). A) Aneuploid profile of tumor T52, B) diploid profile of tumor T221, C) diploid-like profile of tetraploid tumor T190, D) copy number pattern in 3.5 N highly aberrant fraction from aneuploidy tumor T210 (gray) superimposed on pattern found in 2N non-aberrant fraction from the same tumor (red) showing only common CNVs (arrows), E) copy number pattern in 2N highly aberrant fraction from diploid tumor T221 shown in green, F) copy number pattern in 4N aberrant fraction from tetraploid tumor T190 (blue) superimposed on pattern in 2N non-aberrant fraction from the same tumor (red) showing only common CNVs (arrows).