Haplotype class | Africa | America | Asia | Europe |
---|
Reference Sequence | NS | 3×10-4; high | 0.009; high | 2×10-26; high |
Class 1 | NS | NS | 9×10-16; high | NS |
Class 2 | NS | 1×10-6; low | 1×10-8; low | 1×10-18; low |
Exchange 1 | - | 0.003; high | - | NS |
Exchange 2 | NS | NS | 0.045; low | 3×10-4; low |
- p-values and direction of significant associations obtained for Chi Square or Cochran-Armitage tests (Additional file 1: Table S3) comparing DEFA1A3 haplotype class with DEFA1A3 copy number, based on the 1000 Genomes samples. All p-values were adjusted for multiple testing using Bonferroni correction. NS = not significant. - = no test performed (see Additional file 1: Table S3). High = associated with a high DEFA1A3 copy number; Low = associated with a low DEFA1A3 copy number.