Skip to main content

Advertisement

Table 1 Alignment of the HLA-B sequence and genotype in 96 samples

From: A Bead-based Normalization for Uniform Sequencing depth (BeNUS) protocol for multi-samples sequencing exemplified by HLA-B

Sample HLA-B SSO HLA-B PSP* Depth Note
Allele 1 Allele 2 Allele 1 Allele 2 Allele 1 Allele 2
0554 HLA-B*44:03 HLA-B*40:06 HLA-B*44:03:01:01 HLA-B*40:06:01:01 1543.4 1114.5  
0555 HLA-B*40:01 HLA-B*44:03 HLA-B*40:01:02 HLA-B*44:03:01 2228.5 2084.8  
0556 HLA-B*13:01 HLA-B*46:01 HLA-B*13:01:01 HLA-B*46:01:01 860.5 765  
0560 HLA-B*13:01 HLA-B*51:01 HLA-B*13:01:01 HLA-B*51:01:01 1416.5 1455.9  
0605 HLA-B*52:01 HLA-B*52:01 HLA-B*52:01:01:02 HLA-B*52:01:01:02 6928.7 Homozygous
0607 HLA-B*07:02 HLA-B*07:02 HLA-B*07:02:01 HLA-B*07:02:01 7357.3 Homozygous
0616 HLA-B*40:02 HLA-B*52:01 HLA-B*40:02:01 HLA-B*52:01:01:02 513.2 500.6  
0639 HLA-B*40:06 HLA-B*35:01 HLA-B*40:06:01:01 HLA-B*35:01:01:02 1758 1656.8  
0642 HLA-B*40:01 HLA-B*35:01 HLA-B*40:01:02 HLA-B*35:01:01:02 2016.8 1545.3  
0645 HLA-B*54:01 HLA-B*54:01 HLA-B*54:01:01 HLA-B*54:01:01 6537 Homozygous
0649 HLA-B*55: 02 HLA-B*40:02 HLA-B*55:02:01 HLA-B*40:02:01 1402.3 1635.5  
0652 HLA-B*15:01 HLA-B*35:01 HLA-B*15:01:01:01 HLA-B*35:01:01:02 2395.4 2308.4  
0658 HLA-B*56:01 HLA-B*44:03 HLA-B*56:01:01 HLA-B*44:03:01 1686.7 2074  
0663 HLA-B*13:01 HLA-B*52:01 HLA-B*13:01:01 HLA-B*52:01:01:02 1538.1 1455.7  
0666 HLA-B*54:01 HLA-B*38:02 HLA-B*54:01:01 HLA-B*38:02:01 2105 1790.8  
0703 HLA-B*55:02 HLA-B*40:06 HLA-B*55:02:01 HLA-B*40:06:01:01 1173.1 1445.3  
0735 HLA-B*44:03 HLA-B*38:02 HLA-B*44:03:01 HLA-B*38:02:01 2507.5 1998.5  
0739 HLA-B*40:02 HLA-B*48:01 HLA-B*40:02:01 HLA-B*48:01:01 1947.1 2382.9  
0741 HLA-B*59:01 HLA-B*07:02 HLA-B*59:01:01:01 HLA-B*07:02:01 1458.6 2336  
0772 HLA-B*07:02 HLA-B*48:01 HLA-B*07:02:01 HLA-B*48:01:01 3512.9 3425  
0779 HLA-B*44:02 HLA-B*39:01 HLA-B*44:02:01:01 HLA-B*39:01:01:03 1677.5 1060.6  
0784 HLA-B*40:06 HLA-B*15:01 HLA-B*40:06:01:01 HLA-B*15:01:01:01 1875.1 1820.8  
0785 HLA-B*52:01 HLA-B*51:01 HLA-B*52:01:01:01 HLA-B*51:01:01 6041.4 6018.4 Onlu 4 heterozygous SNVs
0810 HLA-B*40:02 HLA-B*46:01 HLA-B*40:02:01 HLA-B*46:01:01 560.8 546.8  
0815 HLA-B*35:01 HLA-B*07:02 HLA-B*35:01:01 HLA-B*07:02:01 1239.5 1740  
0821 HLA-B*40:01 HLA-B*40:02 HLA-B*40:01:02 HLA-B*07:02:01 1239.5 1740  
0821 HLA-B*40:01 HLA-B*40:02 HLA-B*40:01:02 HLA-B*40:02:01 2144.4 1925.5  
0822 HLA-B*54:01 HLA-B*35:01 HLA-B*54:01:01 HLA-B*35:01:01 1550 1840.6  
0823 HLA-B*15:11 HLA-B*07:02 HLA-B*15:11:01 HLA-B*07:02:01 703.5 914.6  
0830 HLA-B*51:01 HLA-B*48:01 HLA-B*51:01:01 HLA-B*48:01:01 1833.8 2509  
0969 HLA-B*40:06 HLA-B*51:01 HLA-B*40:06:01:01 HLA-B*51:01:01 1575.4 1650.4  
0975 HLA-B*44:03 HLA-B*07:02 HLA-B*44:03:01 HLA-B*07:02:01 180.4 209.3  
0976 HLA-B*54:01 HLA-B*35:01 HLA-B*54:01:01 HLA-B*35:01:01 3635.9 3759.2  
0977 HLA-B*44:02 HLA-B*15:18 HLA-B*44:02:01:01 HLA-B*15:18:01 722.2 574.4  
0979 HLA-B*39:01 HLA-B*39:01 HLA-B*39:01:01:03 HLA-B*39:01:03 2128 2125.7 Only 1 heterozygous SNV
0991 HLA-B*15:01 HLA-B*39:01 HLA-B*15:01:01 HLA-B*39:01:01:03 1685.4 1551.3  
0997 HLA-B*15:01 HLA-B*51:01 HLA-B*15:01:01:01 HLA-B*39:01:01:03 1685.4 1551.3  
0997 HLA-B*15:01 HLA-B*51:01 HLA-B*15:01:01 HLA-B*51:01:01 2588 2692.1  
0999 HLA-B*48:01 HLA-B*39:01 HLA-B*48:01:01 HLA-B*39:01:01:03 1470.4 1045.3  
1009 HLA-B*54:01 HLA-B*39:01 HLA-B*54:01:01 HLA-B*39:01:01:03 326.8 294.7  
1011 HLA-B*52:01 HLA-B*07:02 HLA-B*52:01:01:02 HLA-B*07:02:01 730.9 943.7  
1012 HLA-B*35:01 HLA-B*48:01 HLA-B*35:01:01:02 HLA-B*48:01:01 1830.1 2482.1  
1013 HLA-B*54:01 HLA-B*52:01 HLA-B*54:01:01 HLA-B*52:01:01:02 533.9 600.7  
1014 HLA-B*55:02 HLA-B*51:01 HLA-B*55:02:01 HLA-B*51:01:01 970.1 1153.1  
1016 HLA-B*44:03 HLA-B*35:01 HLA-B*44:03:01 HLA-B*35:01:01 739.7 655.5  
1018 HLA-B*46:01 HLA-B*15:01 HLA-B*46:01:01 HLA-B*15:01:01:01 5360.8 5496.1 Only 7 heterozygous SNVs
1030 HLA-B*40:06 HLA-B*07:02 HLA-B*40:06:01:01 HLA-B*07:02:01 1638.8 2668.6  
1045 HLA-B*15:11 HLA-B*35:01 HLA-B*15:11:01 HLA-B*35:01:01:02 1597.5 1448.8  
1056 HLA-B*58:01 HLA-B*67:01 HLA-B*58:01:01 HLA-B*67:01:01 2497.9 2214.5  
1057 HLA-B*40:02 HLA-B*40:02 HLA-B*40:02:01 HLA-B*40:02:01 4113.6 Homozygous
1064 HLA-B*40:06 HLA-B*51:01 HLA-B*40:06:01:01 HLA-B*51:01:01 963.5 1048.8  
1065 HLA-B*54:01 HLA-B*52:01 HLA-B*54:01:01 HLA-B*52:01:01:02 1213.9 1563.8  
1071 HLA-B*56:01 HLA-B*40:06 HLA-B*56:01:01 HLA-B*40:06:01:01 4061.2 1223  
1079 HLA-B*40:02 HLA-B*39:01 HLA-B*40:02:01 HLA-B*39:01:03 2319.8 1507.5  
1082 HLA-B*40:01 HLA-B*51:01 HLA-B*40:01:02 HLA-B*51:01:01 639.3 542.7  
1083 HLA-B*59:01 HLA-B*54:01 HLA-B*59:01:01 HLA-B*54:01:01 716.5 1208.2  
1087 HLA-B*44:03 HLA-B*07:02 HLA-B*44:03:01 HLA-B*07;02:01 1975.5 2605.1  
1095 HLA-B*40:02 HLA-B*54:01 HLA-B*40:02:01 HLA-B*51:01:01 946.4 962.2  
1097 HLA-B*40:01 HLA-B*40:06 HLA-B*40:01:02 HLA-B*40:06:01:01 2642.2 1822.5  
1110 HLA-B*40:01 HLA-B*51:01 HLA-B*40:01:02 HLA-B*51:01:01 1277.1 1156.9  
1111 HLA-B*54:01 HLA-B*40:03 HLA-B*54:01:01 HLA-B*40:03 831.3 943.7  
1116 HLA-B*52:01 HLA-B*07:02 HLA-B*52:01:01:02 HLA-B*07:02:01 981.1 1535.6  
1117 HLA-B*52:01 HLA-B*51:01 HLA-B*52:01:01:02 HLA-B*51:01:01 5900.6 6084.9 Only 3 heterozygous SNVs
1119 HLA-B*35:01 HLA-B*07:02 HLA-B*35:01:01:02 HLA-B*07:02:01 921.3 1370.1  
1129 HLA-B*59:01 HLA-B*40:02 HLA-B*59:01:01:01 HLA-B*40:02:01 1472.9 2178.5  
1131 HLA-B*44:03 HLA-B*52:01 HLA-B*44:03:01 HLA-B*52:01:01:02 1519.9 1456.8  
1142 HLA-B*40:02 HLA-B*39:04 HLA-B*40:02:01 HLA-B*39:04 1253 886.5  
1144 HLA-B*44:03 HLA-B*15:11 HLA-B*44:03:01 HLA-B*15:11:01 1061.7 993.2  
1149 HLA-B*44:03 HLA-B*52:01 HLA-B*44:03:01 HLA-B*52:01:01:02 719.6 633.6  
1154 HLA-B*59:01 HLA-B*40:02 HLA-B*59;01:01:01 HLA-B*40:02:01 146.2 171.8  
1157 HLA-B*35:01 HLA-B*48:01 HLA-B*35:01:01:02 HLA-B*48:01:01 911 1077.3  
1160 HLA-B*59:01 HLA-B*54:01 HLA-B*59:01:01:02 HLA-B*54:01:01 129.8 166.8  
1161 HLA-B*55:02 HLA-B*51:01 HLA-B*55:02:01 HLA-B*51:01:01 402.5 366.6  
1163 HLA-B*56:01 HLA-B*46:01 HLA-B*56:01:01 HLA-B*46:01:01 2048.1 2276.5  
1165 HLA-B*15:01 HLA-B*07:02 HLA-B*15:01:01:01 HLA-B*07:02:01 688.1 907.3  
1167 HLA-B*40:06 HLA-B*52:01 HLA-B*40:06:01:01 HLA-B*52:01:01:02 1486.7 4508.1  
1169 HLA-B*54:01 HLA-B*54:01 HLA-B*54:01:01 HLA-B*54:01:01 7086.1 Homozygous
1171 HLA-B*54:01 HLA-B*44:03 HLA-B*54:01:01 HLA-B*44:03:01 1586.6 1833.9  
1175 HLA-B*15:11 HLA-B*15:01 HLA-B*15:11:01 HLA-B*HLA-B*15:01::01:01 5717.6 5693 Only 3 heterozygous SNVs
1182 HLA-B*55:02 HLA-B*51:01 HLA-B*55:02:01 HLA-B*51:01:01 1156.6 1451.5  
1183 HLA-B*54:01 HLA-B*35:01 HLA-B*54:01:01 HLA-B*35:01:01 1413.5 1537.7  
1184 HLA-B*52:01 HLA-B*52:01 HLA-B*52:01:01:02 HLA-B*52:01:01:02 6701.3 Homozygous
1199 HLA-B*51:01 HLA-B*51:01 HLA-B*51:01:01 HLA-B*51:01:01 5229.1 Homozygous
1201 HLA-B*44:03 HLA-B*52:01 HLA-B*44:03:01 HLA-B*52:01:01:02 1990.6 1665.9  
1203 HLA-B*54:01 HLA-B*52:01 HLA-B*54:01:01 HLA-B*52:01:01:02 1246.4 1313.2  
1217 HLA-B*40:01 HLA-B*46:01 HLA-B*40:01:02 HLA-B*46:01:01 2225.1 1882.2  
1224 HLA-B*40:02 HLA-B*40:03 HLA-B*40:02:01 HLA-B*40:03 6306.5 6286.4 Only 3 heterozygous SNVs
1225 HLA-B*40:01 HLA-B*44:03 HLA-B*40:01:02 HLA-B*44:03:01 1554 1399.6  
1229 HLA-B*52:01 HLA-B*52:01 HLA-B*52:01:01:02 HLA-B*52:01:01:02 6748.5 Homozygous
1234 HLA-B*44:03 HLA-B*40:06 HLA-B*44:03:01 HLA-B*40:06:01:01 2490.3 1715.9  
1236 HLA-B*54:01 HLA-B*40:06 HLA-B*54:01:01 HLA-B*40:06:01:01 1132.4 1244.4  
1238 HLA-B*40:02 HLA-B*67:01 HLA-B*40:02:01 HLA-B*67:01:01 2040.9 1691  
1239 HLA-B*40:03 HLA-B*51:01 HLA-B*40:03 HLA-B*51:01:01 1787 1789.8  
1250 HLA-B*44:03 HLA-B*51:01 HLA-B*44:03:01 HLA-B*51:01:01 357.7 317.8  
1259 HLA-B*40:02 HLA-B*07:02 HLA-B*40:02:01 HLA-B*07:02:01 1346.9 1934.4  
1260 HLA-B*40:06 HLA-B*35:01 HLA-B*40:06:01:01 HLA-B*35:01:01:02 641.9 680.8  
1265 HLA-B*40:01 HLA-B*40:06 HLA-B*40:01:02 HLA-B*40:06:01:01 2226.2 1691.7  
  1. *Phase defined sequencing pipeline.