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Figure 8 | BMC Genomics

Figure 8

From: A systems biology approach identified different regulatory networks targeted by KSHV miR-K12-11 in B cells and endothelial cells

Figure 8

Interferon responses were repressed via the interplay of multiple signaling pathways and transcription factors. MiR-K12-11 targeted cytokine receptors and TFs, both of which affected a variety of interferon stimulated genes (ISGs). Through direct and indirect impact, miR-K12-11 is able to modulate the host innate immune response and to help KSHV to establish latency.

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BMC Genomics

ISSN: 1471-2164

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