Effect of LNA-122i treatment on hepatic omy-miRNA-122 isomiRNA expression (A-C), expression of hepatic, non-targeted omy-miRNA species (D-F) and hepatic mRNAs predicted in silico to be targeted by omy-miRNA-122 isomiRNAs (G-I). Analyzed groups consisted of n = 6 samples and data are depicted as mean ± S.E.M. for each group. Data were analyzed using one-way ANOVA and differences between individual experimental groups assessed by Student-Newman-Keuls post-hoc test. Different letters indicate a significant difference (p < 0.05) between experimental groups.