Table 6 Developmentally regulated genes in purified macrophages from WT mice
Gene Name | Fold-change: PND 3 vs 0 | Gene Name | Fold-change: PND 10 vs 3 | Gene Name | Fold-change: PND 42 vs 10 | |||
|---|---|---|---|---|---|---|---|---|
WT | Scnn1b-Tg | WT | Scnn1b-Tg | WT | Scnn1b-Tg | |||
UP-REGULATED | ||||||||
Fabp1 | 42.2 | 8.6 | Ear11 | 39.5 | 10.5 | Spag11b | 23.8 | 21.0 |
Coro6 | 24.3 | 3.0 | Fbp1 | 18.0 | 3.8 | Cpne5 | 18.7 | 7.0 |
Treml4 | 24.1 | 13.2 | Ccl24 | 12.2 | 4.6 | Slc9a2 | 10.2 | 2.5 |
Rnase6 | 14.1 | 6.0 | Retnlg | 12.0 | -2.1 | Lrg1 | 7.4 | 3.1 |
F630028O10Rik* | 13.5 | 12.3 | Retnla | 9.8 | 1.0 | Pnpla5 | 6.5 | 2.0 |
Gm4070 | 10.8 | 4.7 | Ccl17 | 9.4 | 5.0 | Ucp3 | 6.4 | 5.8 |
AW112010 | 10.6 | 13.9 | Alox15 | 4.3 | 1.9 | Epcam | 6.2 | 1.5 |
Mcoln3 | 9.4 | 18.6 | Arg1 | 4.1 | -1.8 | Gca | 5.4 | 3.1 |
Gbgt1 | 8.6 | 8.3 | Prg2 | 3.6 | 1.4 | 5730507C01Rik | 5.4 | 3.5 |
Irg1 | 8.5 | 118.2 | Ch25h | 3.3 | 3.9 | D630039A03Rik | 5.3 | 6.2 |
Alox5 | 8.5 | 4.1 | H2-Ab1 | 3.1 | 2.2 | Gm26154* | 4.8 | 1.5 |
2010016I18Rik | 8.4 | 6.5 | H2-Aa | 3.0 | 2.0 | Cd74 | 4.8 | 5.9 |
Rab44 | 8.3 | 3.1 | Il13 | 3.0 | 1.4 | Gal | 4.8 | 2.1 |
Cfb | 8.3 | 11.4 | Mmp12 | 3.0 | 1.9 | H2-Ab1 | 4.7 | 5.8 |
Fpr1 | 8.0 | 15.5 | Serpine1 | 2.9 | 1.6 | Tnfsf13b | 4.6 | -1.1 |
DOWN-REGULATED | ||||||||
Agr2 | -223.2 | -171.4 | Hp | -10.4 | -5.4 | Ear11 | -44.3 | 14.0 |
Chad | -105.2 | -163.4 | Scgb1a1 | -9.7 | -4.1 | Fbp1 | -19.1 | 15.8 |
Muc5b | -83.9 | -113.5 | Saa3 | -8.6 | -51.9 | S100a9 | -16.8 | -3.0 |
Meg3* | -65.4 | -84.1 | Irg1 | -7.8 | -6.3 | Arg1 | -14.3 | 2.4 |
Lypd2 | -64.7 | -83.5 | Scgb3a1 | -6.7 | -8.2 | Retnlg | -14.0 | 1.6 |
Muc16 | -63.4 | -83.4 | Reg3g | -6.3 | -10.5 | Retnla | -13.7 | 10.6 |
Gp2 | -60.9 | -92.3 | Xist* | -6.2 | -9.8 | Ccl24 | -12.6 | 3.8 |
Krt7 | -60.1 | -51.7 | Clec4e | -5.4 | -1.7 | Mmp12 | -10.1 | -1.2 |
Atp1b1 | -58.6 | -56.7 | Slc4a1 | -5.3 | -4.6 | AA467197 | -7.6 | 1.0 |
Igf2 | -57.4 | -78.0 | Rsad2 | -5.1 | -3.5 | AB124611 | -6.3 | -2.9 |
H19* | -57.3 | -137.5 | Mmp14 | -4.8 | -1.8 | Ldhb | -6.0 | -5.1 |
Msln | -54.2 | -7.1 | BC100530 | -4.7 | -3.1 | Tarm1 | -5.9 | -1.5 |
Clic3 | -53.7 | -5.9 | Alas2 | -4.1 | -3.1 | Itgam | -5.8 | -2.4 |
AU021092 | -52.9 | -5.7 | Gm5416 | -4.0 | -36.8 | Ebi3 | -5.8 | -4.6 |
BC048546 | -52.9 | -5.7 | Gypa | -4.0 | -3.2 | Alox15 | -5.6 | 3.5 |