Table 7 Developmentally regulated genes in purified macrophages from Scnn1b- Tg mice
Gene Name | Fold change: PND 3 vs 0 | Gene Name | Fold change: PND 10 vs 3 | Gene Name | Fold change: PND 42 vs 10 | |||
|---|---|---|---|---|---|---|---|---|
Scnn1b-Tg | WT | Scnn1b-Tg | WT | Scnn1b-Tg | WT | |||
UP-REGULATED | ||||||||
Irg1 | 118.2 | 8.5 | Ear11 | 10.5 | 39.5 | Rbp4 | 69.2 | -1.8 |
Saa3 | 55.5 | 5.5 | Fabp1 | 6.7 | 2.4 | Spag11b | 21.0 | 23.8 |
Clec4e | 52.9 | 8.0 | Ccl17 | 5.0 | 9.4 | Fbp1 | 15.8 | -19.1 |
Gpr84 | 40.7 | 3.5 | Ccl24 | 4.6 | 12.2 | Ear11 | 14.0 | -44.3 |
Inhba | 39.3 | 1.8 | Coro6 | 4.3 | 1.8 | Awat1 | 13.4 | -3.4 |
Gm5416 | 32.3 | -1.6 | Ch25h | 3.9 | 3.3 | Bex1 | 12.8 | -1.5 |
Il1f9 | 32.2 | 3.6 | Sorbs3 | 3.8 | 2.4 | Retnla | 10.6 | -13.7 |
Cxcl3 | 26.2 | 1.9 | Fbp1 | 3.8 | 18.0 | Sox7 | 10.0 | -1.1 |
Slc11a1 | 23.2 | 2.2 | Sftpc | 3.2 | 1.0 | Lhx2 | 9.5 | -1.2 |
Pla2g7 | 23.1 | 4.3 | Ear5 | 3.2 | 2.4 | Scgb1a1 | 8.5 | 3.2 |
Ccrl2 | 21.5 | 4.6 | Map1b | 3.1 | -1.1 | Slc1a2 | 7.8 | 1.0 |
Mcoln3 | 18.6 | 9.4 | Ffar4 | 3.0 | 1.8 | Arnt2 | 7.2 | 1.0 |
Aoah | 18.3 | 3.9 | Pdk4 | 2.9 | 1.6 | Cpne5 | 7.0 | 18.7 |
Slc7a11 | 17.6 | 5.3 | Htr2c | 2.9 | 2.2 | Scd1 | 6.9 | 1.6 |
Cxcl1 | 17.0 | 1.1 | Mamdc2 | 2.9 | 1.4 | Ear5 | 6.8 | -1.0 |
DOWN-REGULATED | ||||||||
Agr2 | -171.4 | -223.2 | Stfa3 | -60.6 | -2.8 | BC100530 | -9.0 | -3.9 |
Chad | -163.4 | -105.2 | Saa3 | -51.9 | -8.6 | Mmp14 | -7.9 | -1.5 |
H19* | -137.5 | -57.3 | Lcn2 | -48.9 | -3.8 | Nt5e | -7.9 | -1.3 |
Tcf21 | -129.7 | -36.3 | Gm5416 | -36.8 | -4.0 | Hp | -7.6 | -1.3 |
Fmo2 | -119.6 | -36.6 | BC100530 | -27.9 | -4.7 | Stfa2l1 | -6.5 | -2.9 |
Muc5b | -113.5 | -83.9 | Stfa2 | -24.4 | -2.6 | Irg1 | -6.2 | 1.0 |
AU021092 | -92.4 | -52.9 | Chi3l1 | -20.0 | -1.7 | Spink2 | -5.9 | -5.0 |
Gp2 | -92.3 | -60.9 | Stfa2l1 | -19.0 | -2.8 | Clec4e | -5.8 | 2.0 |
Meg3* | -84.1 | -65.4 | S100a9 | -18.9 | -1.8 | Cxcl2 | -5.8 | -1.9 |
Lypd2 | -83.5 | -64.7 | Olfm4 | -15.5 | -1.5 | Apoc2 | -5.3 | -2.9 |
Muc16 | -83.4 | -63.4 | Asprv1 | -13.8 | -1.8 | Apoe | -5.2 | -3.8 |
Igf2 | -78.0 | -57.4 | Prok2 | -12.3 | -1.1 | Ldhb | -5.1 | -6.0 |
Acta1 | -76.7 | -2.0 | Thbs1 | -12.2 | -1.8 | Hilpda | -5.0 | -1.2 |
Fhl1 | -72.2 | -21.6 | Il1r2 | -12.0 | -1.4 | Lpcat2 | -4.9 | -1.6 |
BC048546 | -71.2 | -52.9 | Ifitm1 | -11.2 | -1.7 | Sftpc | -4.8 | -1.6 |