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Figure 2 | BMC Genomics

Figure 2

From: Systematic transcriptome analysis of the zebrafish model of diamond-blackfan anemia induced by RPS24 deficiency

Figure 2

RPS24 is required for both primitive and definitive hematopoiesis zebrafish partly mediated by p53 pathway. (A-C) The expression of gata1 (black arrow) was significantly decreased in rps24 MO and can be partly rescued in rps24 and p53 double MO at 48 hpf. (D-F) The expression of scl was significantly decreased in rps24 MO and can be partly rescued in rps24 and p53 double MO at 48 hpf. (G-L) The expression of cmyb and runx1 was significantly decreased in rps24 MO and can be partly rescued in rps24 and p53 double MO at 48 hpf.

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