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Figure 6 | BMC Genomics

Figure 6

From: Identification of male-specific amh duplication, sexually differentially expressed genes and microRNAs at early embryonic development of Nile tilapia (Oreochromis niloticus)

Figure 6

Genomic sequences and predicted polypeptides of amh and amhy genes. The coding region of the 7th exon of the AMH gene is aligned with sequences of XX-female amh and YY-male amhy. Sequences derived from GenBank entries were aligned (Accession Nos. XM_003451305, HG518787, HG518784 for amh reference gene, female amh and male amhy, respectively). Above the sequences, Roman numerals label the genomic element of the gene. Asterisks below the sequences denote identical residues in all three sequence submissions. Dashes mark gaps introduced by the alignment program. The shadowed regions localize the TGF-β domain. Numbers indicating the position of the last residue within the GenBank entry are added at right ends of rows. (A) Genomic sequences: The end of intron 6 is shown in lower-case italic letters and the last two bases of the acceptor splice site (ag) are in bold type. The in frame stop codons (TAG or TAA) are in bold and underlined type. (B) Predicted polypeptides: Below the sequences, conserved substitutions are indicated by two dots; and semi-conserved substitutions are indicated by dots. Cysteine residues that form disulfide bonds according to TGF-β family signature (PROSITE PDOC00223) are in white against purple background and this signature layout is delineated above the TGF-β domain sequence.

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