Figure 1
From: Haploinsufficiency of ETV6 and CDKN1B in patients with acute myeloid leukemia and complex karyotype
Interstitial 12p13 deletions. ArrayCGH results (244 k, Agilent) showing interstitial 12p13 deletions in six patients. The genomic profiles are zoomed in to the minimal deleted region covering ETV6 at the telomeric site and CDKN1B at the centromeric site. Deleted regions are highlighted in gray. Next to the breakpoint region given in Mb, the size of the deletion is shown. The ETV6 gene is orientated in 5′-3′ direction. Mean log ratios of the deletions correlate with the clone size according to karyotyping.