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Table 2 Differentially expressed GPCRs and channels in the brains of sexually mature male eels

From: Changes in the gene expression profiles of the brains of male European eels (Anguilla anguilla) during sexual maturation

Direction

Fold change

Protein description

Type

+

1.66

Extracellular calcium-sensing receptor-like [Oreochromis niloticus]

GPCR (Glutamate)

+

2.07

5-hydroxytryptamine receptor 1B-like [Oryzias latipes]

GPCR (Rhodopsin)

+

6.15

G-protein coupled receptor 64-like [Maylandia zebra]

GPCR (Secretin)

+

2.37

Probable G-protein coupled receptor 125-like [Maylandia zebra]

GPCR (Secretin)

-

0.64

Probable G-protein coupled receptor 148-like [Oreochromis niloticus]

GPCR (Glutamate)

-

0.50

Metabotropic glutamate receptor 5-like [Danio rerio]

GPCR (Glutamate)

-

0.59

Metabotropic glutamate receptor 5-like [Oreochromis niloticus]

GPCR (Glutamate)

+

3.20

Sodium channel protein type 4 subunit alpha B-like [Maylandia zebra]

Channel

+

1.91

Sodium channel protein type 2 subunit alpha-like isoform 7 [Gallus gallus]

Channel

+

1.60

Voltage-dependent anion-selective channel protein 1 [Danio rerio]

Channel

+

1.74

Voltage-dependent anion-selective channel protein 2 [Salmo salar]

Channel

+

1.66

Voltage-dependent anion-selective channel protein 2 [Danio rerio]

Channel

+

1.60

Gamma-aminobutyric acid receptor subunit delta-like [Oreochromis niloticus]

Channel

+

5.68

Cyclic nucleotide-gated cation channel alpha-3-like [Danio rerio]

Channel

-

0.64

Potassium voltage-gated channel subfamily C member 2-like [Oreochromis niloticus]

Channel

-

0.63

Voltage-gated potassium channel subunit beta-1-like [Danio rerio]

Channel

-

0.62

Calcium-activated potassium channel subunit alpha-1-like [Xenopus tropicalis]

Channel

-

0.50

Sodium channel protein type 2 subunit alpha-like partial [Takifugu rubripes]

Channel

  1. G protein-coupled receptors (GPCRs) were assigned to families based on the GRAFS classification system [25]. Genes that have positive direction values were up-regulated in the brains of sexually mature male eels in comparison to immature males while those that are negative were down-regulated in this group. Gene descriptions are based on BLASTX hits in RefSeq proteins. A false discovery rate of 0.05 was used to identify differentially expressed genes.