Validation of smRNA-seq data. (A) Heat maps of miRNAs dominantly expression in early EPC (left), late EPC (middle), and mature EC (right) with at least a 1.5 fold change. (B) RT-qPCR (qPCR) validation of smRNA-seq (Seq) results. Histograms of qPCR results were graphed as mean ± standard deviation (n = 3) ***: p < 0.001. (C) Pearson’s correlation result between smRNA-seq and qPCR data.