Table 4 Enzymatic functions exclusively found in our re-annotation comparatively to S. cerevisiae (functions that were also found exclusively in our re-annotation comparatively to K. lactis are in italic; for each EC number the information source that was used to collect it is presented)

1.13.99.1

Inositol oxygenase

myo-inositol + O₂ = D-glucuronate + H₂O

Uniprot

1.14.11.1

Gamma-butyrobetaine dioxygenase

4-trimethylammoniobutanoate + 2-oxoglutarate + O₂ = 3-hydroxy-4-trimethylammoniobutanoate + succinate + CO₂

merlin

1.14.11.8

Trimethyllysine dioxygenase

N6,N6,N6-trimethyl-L-lysine + 2-oxoglutarate + O₂ = 3-hydroxy-N6,N6,N6-trimethyl-L-lysine + succinate + CO₂

Uniprot

1.14.19.4

Δ8-fatty-acid desaturase

phytosphinganine + reduced acceptor + O₂ = Delta8-phytosphingenine + acceptor + 2 H₂O

merlin

1.14.19.6

Δ12-fatty-acid desaturase

acyl-CoA + reduced acceptor + O₂ = Delta12-acyl-CoA + acceptor + 2 H₂O

merlin

1.4.3.21

Primary-amine oxidase

RCH₂NH₂ + H₂O + O₂ = RCHO + NH₃ + H₂O₂

Uniprot

2.1.1.79

Cyclopropane synthetase

S-adenosyl-L-methionine + phospholipid olefinic fatty acid = S-adenosyl-L-homocysteine + phospholipid cyclopropane fatty acid

merlin

2.4.1.80

Ceramide glucosyltransferase

UDP-glucose + N-acylsphingosine = UDP + D-glucosyl-N-acylsphingosine

merlin

3.2.1.96

Endo-beta-N-acetylglucosaminidase

Endohydrolysis of the N,N'-diacetylchitobiosyl unit in high-mannose glycopeptides and glycoproteins containing the -[Man(GlcNAc)2]Asn- structure.

Uniprot

3.5.2.2

Dihydropyrimidinase

5,6-dihydrouracil + H₂O = 3-ureidopropanoate

merlin

3.5.3.11

Agmatinase

agmatine + H₂O = putrescine + urea

AGD

3.5.99.6

Glucosamine-6-phosphate deaminase

D-glucosamine 6-phosphate + H₂O = D-fructose 6-phosphate + NH₃

AGD

4.6.1.13

Phosphatidylinositol diacylglycerol-lyase

1-phosphatidyl-1D-myo-inositol = 1D-myo-inositol 1,2-cyclic phosphate + 1,2-diacyl-sn-glycerol

merlin