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Table 3 Distribution of hypermethylation and hypomethylation in each gene elements

From: Dysregulation of genome-wide gene expression and DNA methylation in abnormal cloned piglets

Category Hypermethylationa Hypomethylationb
Upstream 2 kb 30c 62
5′UTR 3 7
CDS 134 253
Intron 425 1219
3′UTR 10 21
Downstream 2 kb 25 64
Total 627 1626
Percentage of reads 10.8% 14.4%
  1. aThe number of methylated reads in the abnormal cloned group was higher than that in the normal group. The number of reads was assessed using chi-square and FDR statistical methods; p < 0.05 was considered significant.
  2. bThe number of methylated reads in the abnormal cloned group was lower than that in the normal cloned group. The standard evaluation was the same as for hypermethylated genes.
  3. cThe percentage of the reads used to calculate the hypermethylation or hypomethylation in each group was gained from the used reads dividing the whole unique reads. All of the used reads were standardized.