Category | Hypermethylationa | Hypomethylationb |
|---|
Upstream 2Â kb
| 30c | 62 |
5′UTR
| 3 | 7 |
CDS
| 134 | 253 |
Intron
| 425 | 1219 |
3′UTR
| 10 | 21 |
Downstream 2Â kb
| 25 | 64 |
Total
| 627 | 1626 |
Percentage of reads
| 10.8% | 14.4% |
- aThe number of methylated reads in the abnormal cloned group was higher than that in the normal group. The number of reads was assessed using chi-square and FDR statistical methods; p < 0.05 was considered significant.
- bThe number of methylated reads in the abnormal cloned group was lower than that in the normal cloned group. The standard evaluation was the same as for hypermethylated genes.
- cThe percentage of the reads used to calculate the hypermethylation or hypomethylation in each group was gained from the used reads dividing the whole unique reads. All of the used reads were standardized.
